Zvavahera Chirenje, MD

Adjunct Professor
Ob/Gyn, Reproductive Sciences
+1 263 470-4890

• Professor (full time) University of California San Francisco, Dept of Obstetrics, Gynaecology & Reproductive Sciences, San Francisco, USA
• Professor (voluntary) University of Zimbabwe Faculty of Medicine & Health Sciences, Harare Zimbabwe
• Principal Investigator (PI) / Director for the University of Zimbabwe Clinical Trials Unit (UZ-UCSF CTU)

In 1994, Dr. Chirenje was one of the founding members of the US National Institutes of Health (NIH) funded University of Zimbabwe - Clinical Trials Research Centre (UZ-CTRC), formerly University of Zimbabwe - University of California, San Francisco (UZ-UCSF) Collaborative Research Programme in Women’s Health. At this facility he conducts pivotal HIV prevention clinical trials in women with particular emphasis on Pre-Exposure Prophylaxis (PrEP) and HIV vaccine development and was instrumental in the establishment of the first HIV vaccine research capacity in Zimbabwe in 2017.

He oversees a research unit with 276 employees in Harare, Zimbabwe and 5 support staff in San Francisco, CA, providing leadership that promotes high quality research for 4 NIH sponsored networks of ACTG, IMPAACT, HPTN and HVTN. Over the past 26 years, Dr Chirenje has overseen the development of a centralized research support unit that coordinates fiscal management and executes NIH protocols at the highest level of data capture and retention of participants with a solid track record of scientific publications that has assisted in policy implementation for Zimbabwe’s Ministry of Health

His long-standing research focus has included evaluating the optimal performance of cervical cancer screening tests in low resource settings, cervical cancer screening and impact of HIV on HPV infections among women, finding safe and effective biomedical HIV prevention interventions for women, STI testing and treatment. Dr. Chirenje was Principal Investigator for a large protocol that screened 11,000 women in Harare, which became an international milestone study demonstrating the effectiveness of visual inspection with acetic acid (VIA) in screening for cervical cancer in low resource settings.

Areas of interest:
• Evaluation of cervical cancer screening & treatment modalities in low resource settings.
• Implementation of HPV vaccination & HPV testing programmes in low resource settings.
• Evaluation of best biomedical HIV prevention methods among women (conducting pivotal HIV prevention trials on PrEP).
• Conducting HIV vaccine safety & efficacy trials.
• Conducting COVID-19 vaccine safety & efficacy trials.

Publications: 

Vaginal Bacteria and Proinflammatory Host Immune Mediators as Biomarkers of Human Immunodeficiency Virus Acquisition Risk Among African Women.

The Journal of infectious diseases

Srinivasan S, Richardson BA, Wallis JM, Fiedler TL, Strenk SM, Hoffman NG, Proll S, Chirenje ZM, Livant EW, Fredricks DN, Hillier SL, Marrazzo JM

Protein dose-sparing effect of AS01B adjuvant in a randomized preventive HIV vaccine trial of ALVAC-HIV (vCP2438) and adjuvanted bivalent subtype C gp120.

The Journal of infectious diseases

Chirenje ZM, Laher F, Dintwe O, Muyoyeta M, deCamp AC, He Z, Grunenberg N, Laher Omar F, Seaton KE, Polakowski L, Woodward Davis AS, Maganga L, Baden LR, Mayer K, Kalams S, Keefer M, Edupuganti S, Rodriguez B, Frank I, Scott H, Stranix-Chibanda L, Gurunathan S, Koutsoukos M, Van Der Meeren O, DiazGranados CA, Paez C, Andersen-Nissen E, Kublin J, Corey L, Ferrari G, Tomaras G, McElrath MJ, HVTN120 study team

"We chose PrEP because I wanted to be sure that this child my wife was going to conceive was indeed mine." Factors influencing the choice of safer conception methods and experiences with its use: a qualitative study among HIV sero-discordant couples in Zi

BMC public health

Brown JM, Musara P, Gitome S, Chitukuta M, Mataveke B, Chirenda T, Mgodi N, Mutero P, Matubu A, Chareka G, Chasakara C, Murombedzi C, Makurumure T, Hughes CS, Bukusi E, Cohen CR, Shiboski S, Darbes L, Rutherford GW, Chirenje ZM, Mhlanga F

"First was to sit down and bring our minds together". A qualitative study on safer conception decision-making among HIV sero-different couples in Zimbabwe.

Sexual and reproductive health matters

Gitome S, Musara P, Chitukuta M, Mhlanga F, Mateveke B, Chirenda T, Mgodi N, Mutero P, Matubu A, Chareka G, Chasakara C, Murombedzi C, Makurumure T, Smith-Hughes C, Bukusi E, Cohen CR, Shiboski S, Darbes L, Rutherford GW, Chirenje ZM, Brown JM

The Impact of DNA Tumor Viruses in low-to-middle income countries (LMICS): a literature review.

Tumour virus research

Guzha BT, Matubu A, Nyandoro G, Mubata HO, Moyo E, Murewanhema G, Chirenje ZM

Efficient regulatory approval of two novel HIV prevention interventions in a resource-limited setting: experiences from Zimbabwe.

Frontiers in reproductive health

Murombedzi C, Chirinda L, Chareka GT, Chirenje ZM, Mgodi NM

Antenatal depression: Associations with birth and neonatal outcomes among women attending maternity care in Harare, Zimbabwe.

PloS one

Kaiyo-Utete M, Langhaug L, Chingono A, Dambi JM, Magwali T, Henderson C, Chirenje ZM

Strategic actions to advance multipurpose prevention technologies in low- and middle-income countries.

Frontiers in reproductive health

Young Holt B, van der Straten A, Barker T, Chirenje ZM, Cameron AI, Scott C, Casas CP, Romano J

Preventing HIV and achieving pregnancy among HIV sero-different couples: Pilot study of a safer conception intervention in Zimbabwe.

PLOS global public health

Brown JM, Gitome S, Mataveke B, Chirenda T, Matubu A, Chareka G, Chasakara C, Mgodi N, Murombedzi C, Musara P, Makurumure T, Hughes CS, Bukusi E, Cohen CR, Shiboski S, Darbes L, Kahn JG, Rutherford GW, Chirenje ZM, Mhlanga F

Population-Level Correlation Between Incidence of Curable Sexually Transmitted Infections and Human Immunodeficiency Virus (HIV)-1 Among African Women Participating in HIV-1 Pre-Exposure Prophylaxis Trials.

The Journal of infectious diseases

Hunidzarira P, Brown ER, Chirenje ZM, Hillier SL, Marrazzo JM, Palanee-Phillips T, Kiweewa FM, Baeten JM, MTN-003/VOICE and MTN-020/ASPIRE Study Teams

Alignment of PrEP adherence with periods of HIV risk among adolescent girls and young women in South Africa and Zimbabwe: a secondary analysis of the HPTN 082 randomised controlled trial.

The lancet. HIV

Velloza J, Donnell D, Hosek S, Anderson PL, Chirenje ZM, Mgodi N, Bekker LG, Marzinke MA, Delany-Moretlwe S, Celum C

Understanding the public health value and defining preferred product characteristics for therapeutic human papillomavirus (HPV) vaccines: World Health Organization consultations, October 2021-March 2022.

Vaccine

Prudden HJ, Achilles SL, Schocken C, Broutet N, Canfell K, Akaba H, Basu P, Bhatla N, Chirenje ZM, Delany-Moretlwe S, Denny L, Gamage DG, Herrero R, Hutubessy R, Villa LL, Murillo R, Schiller JT, Stanley M, Temmerman M, Zhao F, Ogilvie G, Kaslow DC, Dull P, Gottlieb SL, Therapeutic HPV Vaccine PPC Expert Consultation Group*

Patient experiences of living with cancer before interaction with palliative care services in Zimbabwe: A qualitative secondary data analysis.

European journal of cancer care

Dandadzi A, Chapman E, Chirenje ZM, Namukwaya E, Pini S, Nkhoma K, Allsop MJ

Prevalent human papillomavirus infection increases the risk of HIV acquisition in African women: advancing the argument for human papillomavirus immunization.

AIDS (London, England)

Liu G, Mugo NR, Brown ER, Mgodi NM, Chirenje ZM, Marrazzo JM, Winer RL, Mansoor L, Palanee-Phillips T, Siva SS, Naidoo L, Jeenarain N, Gaffoor Z, Nair GL, Selepe P, Nakabiito C, Mkhize B, Mirembe BG, Taljaard M, Panchia R, Baeten JM, Balkus JE, Hladik F, Celum CL, Barnabas RV

The IARC Perspective on Cervical Cancer Screening.

The New England journal of medicine

Bouvard V, Wentzensen N, Mackie A, Berkhof J, Brotherton J, Giorgi-Rossi P, Kupets R, Smith R, Arrossi S, Bendahhou K, Canfell K, Chirenje ZM, Chung MH, Del Pino M, de Sanjosé S, Elfström M, Franco EL, Hamashima C, Hamers FF, Herrington CS, Murillo R, Sangrajrang S, Sankaranarayanan R, Saraiya M, Schiffman M, Zhao F, Arbyn M, Prendiville W, Indave Ruiz BI, Mosquera-Metcalfe I, Lauby-Secretan B

Prevalence and Incidence of Sexually Transmitted Infection in Injectable Progestin Contraception Users in South Africa.

Frontiers in reproductive health

Noguchi LM, Marrazzo JM, Richardson B, Hillier SL, Balkus JE, Palanee-Phillips T, Nair G, Panchia R, Piper J, Gomez K, Ramjee G, Chirenje ZM

Self-collected and clinician-collected anal swabs show modest agreement for HPV genotyping.

PloS one

Dube Mandishora RS, Rounge TB, Fitzpatrick M, Christiansen IK, Ambur OH, Lagström S, Stray-Pedersen B, Tommasino M, Palefsky J, Chirenje ZM

Effect of injectable progestin-only contraceptives, depot medroxyprogesterone acetate and norethisterone enanthate, on cytokine production during T-cell activation.

American journal of reproductive immunology (New York, N.Y. : 1989)

Matubu AT, Hillier SL, Meyn LA, Stoner KA, Mhlanga F, Mbizvo M, Maramba A, Chirenje ZM, Achilles SL

Safety, uptake, and use of a dapivirine vaginal ring for HIV-1 prevention in African women (HOPE): an open-label, extension study.

The lancet. HIV

Baeten JM, Palanee-Phillips T, Mgodi NM, Mayo AJ, Szydlo DW, Ramjee G, Gati Mirembe B, Mhlanga F, Hunidzarira P, Mansoor LE, Siva S, Govender V, Makanani B, Naidoo L, Singh N, Nair G, Chinula L, Parikh UM, Mellors JW, Balán IC, Ngure K, van der Straten A, Scheckter R, Garcia M, Peda M, Patterson K, Livant E, Bunge K, Singh D, Jacobson C, Jiao Y, Hendrix CW, Chirenje ZM, Nakabiito C, Taha TE, Jones J, Torjesen K, Nel A, Rosenberg Z, Soto-Torres LE, Hillier SL, Brown ER, MTN-025/HOPE Study Team

Preferences and Acceptability of Vaginal Delivery Forms for HIV Prevention Among Women, Male Partners and Key Informants in South Africa and Zimbabwe: Qualitative Findings.

AIDS and behavior

Musara P, Milford C, Shapley-Quinn MK, Weinrib R, Mutero P, Odoom E, Mgodi NM, Chirenje ZM, Hanif H, Clark MR, Smit J, van der Straten A, Montgomery ET, Quatro Study Team

Estimated costs for the delivery of safer conception strategies for HIV-discordant couples in Zimbabwe: a cost analysis.

BMC health services research

Hughes CS, Brown J, Murombedzi C, Chirenda T, Chareka G, Mhlanga F, Mateveke B, Gitome S, Makurumure T, Matubu A, Mgodi N, Chirenje Z, Kahn JG

Zim CHIC: A cohort study of immune changes in the female genital tract associated with initiation and use of contraceptives.

American journal of reproductive immunology (New York, N.Y. : 1989)

Achilles SL, Meyn LA, Mhlanga FG, Matubu AT, Stoner KA, Beamer MA, Chirenje ZM, Hillier SL

Efficacy is Not Everything: Eliciting Women's Preferences for a Vaginal HIV Prevention Product Using a Discrete-Choice Experiment.

AIDS and behavior

Browne EN, Montgomery ET, Mansfield C, Boeri M, Mange B, Beksinska M, Schwartz JL, Clark MR, Doncel GF, Smit J, Chirenje ZM, van der Straten A

Antenatal depression: an examination of prevalence and its associated factors among pregnant women attending Harare polyclinics.

BMC pregnancy and childbirth

Kaiyo-Utete M, Dambi JM, Chingono A, Mazhandu FSM, Madziro-Ruwizhu TB, Henderson C, Magwali T, Langhaug L, Chirenje ZM

Use of the dapivirine vaginal ring and effect on cervical cytology abnormalities.

AIDS (London, England)

Reddy K, Kelly C, Brown ER, Jeenarain N, Naidoo L, Siva S, Bekker LG, Nair G, Makanani B, Chinula L, Mgodi N, Chirenje Z, Kiweewa FM, Marrazzo J, Bunge K, Soto-Torres L, Piper J, Baeten JM, Palanee-Phillips T, MTN-020/ASPIRE and MTN-003/VOICE Study Teams

Mentored postdoctoral training in Zimbabwe: A report on a successful collaborative effort.

Journal of public health in Africa

Zhou DT, Maponga CC, Madhombiro M, Dube A, Mano R, Nyamhunga A, Machingura I, Manasa J, Hakim J, Chirenje ZM, Mudzviti T, Nhachi C, Ma Q, DiFrancesco R, Masanganise R, Morse GD

Depot medroxyprogesterone acetate and norethisterone enanthate differentially impact T-cell responses and expression of immunosuppressive markers.

American journal of reproductive immunology (New York, N.Y. : 1989)

Matubu A, Hillier SL, Meyn LA, Stoner KA, Mhlanga F, Mbizvo M, Maramba A, Chirenje ZM, Achilles SL

Human papillomavirus genotype distribution in genital warts among women in Harare-Zimbabwe.

Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology

Manyere NR, Dube Mandishora RS, Magwali T, Mtisi F, Mataruka K, Mtede B, Palefsky JM, Chirenje ZM

Social harms in female-initiated HIV prevention method research: state of the evidence.

AIDS (London, England)

Montgomery ET, Roberts ST, Nel A, Malherbe M, Torjesen K, Bunge K, Singh D, Baeten JM, Marrazzo J, Chirenje ZM, Kabwigu S, Beigi R, Riddler SA, Gaffour Z, Reddy K, Mansoor LE, Nair G, Woeber K, Moodley J, Jeenarain N, Siva S, Naidoo L, Govender V, Palanee-Phillips T

Understanding data and information needs for palliative cancer care to inform digital health intervention development in Nigeria, Uganda and Zimbabwe: protocol for a multicountry qualitative study.

BMJ open

Okunade K, Bashan Nkhoma K, Salako O, Akeju D, Ebenso B, Namisango E, Soyannwo O, Namukwaya E, Dandadzi A, Nabirye E, Mupaza L, Luyirika E, Ddungu H, Chirenje ZM, Bennett MI, Harding R, Allsop MJ

Giant mucinous cystadenoma: a case report.

Journal of medical case reports

Gwanzura C, Muyotcha AF, Magwali T, Chirenje ZM, Madziyire MG

Community-based self-collected human papillomavirus screening in rural Zimbabwe.

BMC public health

Fitzpatrick MB, El-Khatib Z, Katzenstein D, Pinsky BA, Chirenje ZM, McCarty K

Tenofovir Gel for Prevention of Herpes Simplex Virus Type 2 Acquisition: Findings From the VOICE Trial.

The Journal of infectious diseases

Marrazzo JM, Rabe L, Kelly C, Richardson B, Deal C, Schwartz JL, Chirenje ZM, Piper J, Morrow RA, Hendrix CW, Marzinke MA, Hillier SL, VOICE Study Team

End-user preference for and choice of four vaginally delivered HIV prevention methods among young women in South Africa and Zimbabwe: the Quatro Clinical Crossover Study.

Journal of the International AIDS Society

Montgomery ET, Beksinska M, Mgodi N, Schwartz J, Weinrib R, Browne EN, Mphili N, Musara P, Jaggernath M, Ju S, Smit J, Chirenje ZM, Doncel GF, van der Straten A

hrHPV prevalence and type distribution in rural Zimbabwe: A community-based self-collection study using near-point-of-care GeneXpert HPV testing.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

Fitzpatrick MB, Dube Mandishora RS, Katzenstein DA, McCarty K, Weber J, Sahoo MK, Manasa J, Chirenje ZM, Pinsky BA

A case of twin reversed arterial perfusion (TRAP) sequence managed conservatively.

The Pan African medical journal

Ziki EM, Chirenje ZM, Madziyire MG

Validation of the GenoType® MTBDRplus Ver 2.0 assay for detection of rifampicin and isoniazid resistance in Mycobacterium tuberculosis complex isolates at UZCHS-CTRC TB research laboratory.

International journal of mycobacteriology

Stephen S, Muzhizhizhi D, Dhibi N, Chidemo T, Samaneka W, Matubu TA, Hakim JG, Chirenje ZM

Anal human papillomavirus infection in HIV-positive men and women at two opportunistic infections clinics in Harare, Zimbabwe.

BMC public health

Chinyowa S, Palefsky JM, Chirenje ZM, Makunike-Mutasa R, Munjoma M, Muguti GI

The association of puerperal sepsis with HIV infection at two tertiary hospitals in Zimbabwe.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

Majangara R, Chirenje ZM, Gidiri MF

HIV infection in patients with sexually transmitted infections in Zimbabwe - Results from the Zimbabwe STI etiology study.

PloS one

Kilmarx PH, Gonese E, Lewis DA, Chirenje ZM, Barr BAT, Latif AS, Gwanzura L, Handsfield HH, Machiha A, Mugurungi O, Rietmeijer CA

The Etiology of Vaginal Discharge Syndrome in Zimbabwe: Results from the Zimbabwe STI Etiology Study.

Sexually transmitted diseases

Chirenje ZM, Dhibi N, Handsfield HH, Gonese E, Tippett Barr B, Gwanzura L, Latif AS, Maseko DV, Kularatne RS, Tshimanga M, Kilmarx PH, Machiha A, Mugurungi O, Rietmeijer CA

Impact of contraceptive initiation on vaginal microbiota.

American journal of obstetrics and gynecology

Achilles SL, Austin MN, Meyn LA, Mhlanga F, Chirenje ZM, Hillier SL

How Presentation of Drug Detection Results Changed Reports of Product Adherence in South Africa, Uganda and Zimbabwe.

AIDS and behavior

Musara P, Montgomery ET, Mgodi NM, Woeber K, Akello CA, Hartmann M, Cheng H, Levy L, Katz A, Grossman CI, Chirenje ZM, van der Straten A, Mensch B, Microbicide Trials Network-003D Study Team

Microbiology and clinical outcomes of puerperal sepsis: a prospective cohort study.

Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology

Majangara R, Gidiri MF, Chirenje ZM

Misreporting of contraceptive hormone use in clinical research participants.

Contraception

Achilles SL, Mhlanga FG, Musara P, Poloyac SM, Chirenje ZM, Hillier SL

The fourth generation AlereTM HIV Combo rapid test improves detection of acute infection in MTN-003 (VOICE) samples.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology

Livant E, Heaps A, Kelly C, Maharaj R, Samsunder N, Nhlangulela L, Karugaba P, Panchia R, Marrazzo J, Chirenje ZM, Parikh UM, VOICE Study Team

Genotypic diversity of anogenital human papillomavirus in women attending cervical cancer screening in Harare, Zimbabwe.

Journal of medical virology

Dube Mandishora RS, Christiansen IK, Chin'ombe N, Duri K, Ngara B, Rounge TB, Meisal R, Ambur OH, Palefsky JM, Stray-Pedersen B, Chirenje ZM

Differences in Cumulative Exposure and Adherence to Tenofovir in the VOICE, iPrEx OLE, and PrEP Demo Studies as Determined via Hair Concentrations.

AIDS research and human retroviruses

Koss CA, Bacchetti P, Hillier SL, Livant E, Horng H, Mgodi N, Mirembe BG, Gomez Feliciano K, Horn S, Liu AY, Glidden DV, Grant RM, Benet LZ, Louie A, van der Straten A, Chirenje ZM, Marrazzo JM, Gandhi M

Risk Factors for Incidence of Sexually Transmitted Infections Among Women in a Human Immunodeficiency Virus Chemoprevention Trial: VOICE (MTN-003).

Sexually transmitted diseases

Chirenje ZM, Gundacker HM, Richardson B, Rabe L, Gaffoor Z, Nair GL, Mirembe BG, Piper JM, Hillier S, Marrazzo J

Contraceptive Use and Pregnancy Incidence Among Women Participating in an HIV Prevention Trial.

Journal of women's health (2002)

Akello CA, Bunge KE, Nakabiito C, Mirembe BG, Fowler MG, Mishra A, Marrazzo J, Chirenje ZM, Celum C, Balkus JE

Adult Hematology and Clinical Chemistry Laboratory Reference Ranges in a Zimbabwean Population.

PloS one

Samaneka WP, Mandozana G, Tinago W, Nhando N, Mgodi NM, Bwakura-Dangarembizi MF, Munjoma MW, Gomo ZA, Chirenje ZM, Hakim JG

Reporting of Adherence in the VOICE Trial: Did Disclosure of Product Nonuse Increase at the Termination Visit?

AIDS and behavior

Mensch BS, Brown ER, Liu K, Marrazzo J, Chirenje ZM, Gomez K, Piper J, Patterson K, van der Straten A

Healthcare providers' perspectives on the acceptability and uptake of HPV vaccines in Zimbabwe.

Journal of psychosomatic obstetrics and gynaecology

Crann SE, Barata PC, Mitchell R, Mawhinney L, Thistle P, Chirenje ZM, Stewart DE

An Empiric HIV Risk Scoring Tool to Predict HIV-1 Acquisition in African Women.

Journal of acquired immune deficiency syndromes (1999)

Balkus JE, Brown E, Palanee T, Nair G, Gafoor Z, Zhang J, Richardson BA, Chirenje ZM, Marrazzo JM, Baeten JM

Corrigendum to "oral and injectable contraceptive use and HIV acquisition risk among women in four African countries: a secondary analysis of data from a microbicide trial" [Contraception 2016; 93 (1): 25-31].

Contraception

Balkus JE, Brown ER, Hillier SL, Coletti A, Ramjee G, Mgodi N, Makanani B, Reid C, Martinson F, Soto-Torres L, Abdool Karim SS, Chirenje ZM

Bone Mineral Density Changes Among Young, Healthy African Women Receiving Oral Tenofovir for HIV Preexposure Prophylaxis.

Journal of acquired immune deficiency syndromes (1999)

Mirembe BG, Kelly CW, Mgodi N, Greenspan S, Dai JY, Mayo A, Piper J, Akello CA, Kiweewa FM, Magure T, Nakabiito C, Marrazzo JM, Chirenje ZM, Riddler SA, MTN-003B Protocol Team

Use of a Vaginal Ring Containing Dapivirine for HIV-1 Prevention in Women.

The New England journal of medicine

Baeten JM, Palanee-Phillips T, Brown ER, Schwartz K, Soto-Torres LE, Govender V, Mgodi NM, Matovu Kiweewa F, Nair G, Mhlanga F, Siva S, Bekker LG, Jeenarain N, Gaffoor Z, Martinson F, Makanani B, Pather A, Naidoo L, Husnik M, Richardson BA, Parikh UM, Mellors JW, Marzinke MA, Hendrix CW, van der Straten A, Ramjee G, Chirenje ZM, Nakabiito C, Taha TE, Jones J, Mayo A, Scheckter R, Berthiaume J, Livant E, Jacobson C, Ndase P, White R, Patterson K, Germuga D, Galaska B, Bunge K, Singh D, Szydlo DW, Montgomery ET, Mensch BS, Torjesen K, Grossman CI, Chakhtoura N, Nel A, Rosenberg Z, McGowan I, Hillier S, MTN-020–ASPIRE Study Team

Oral and injectable contraceptive use and HIV acquisition risk among women in four African countries: a secondary analysis of data from a microbicide trial.

Contraception

Balkus JE, Brown ER, Hillier SL, Coletti A, Ramjee G, Mgodi N, Makanani B, Reid C, Martinson F, Soto-Torres L, Abdool Karim SS, Chirenje ZM

Age-Disparate Partnerships and Risk of HIV-1 Acquisition Among South African Women Participating in the VOICE Trial.

Journal of acquired immune deficiency syndromes (1999)

Balkus JE, Nair G, Montgomery ET, Mishra A, Palanee-Phillips T, Ramjee G, Panchia R, Selepe P, Richardson BA, Chirenje ZM, Marrazzo JM

Risk of HIV-1 acquisition among women who use diff erent types of injectable progestin contraception in South Africa: a prospective cohort study.

The lancet. HIV

Noguchi LM, Richardson BA, Baeten JM, Hillier SL, Balkus JE, Chirenje ZM, Bunge K, Ramjee G, Nair G, Palanee-Phillips T, Selepe P, van der Straten A, Parikh UM, Gomez K, Piper JM, Watts DH, Marrazzo JM, VOICE Study Team

Pharmacological Measures of Treatment Adherence and Risk of HIV Infection in the VOICE Study.

The Journal of infectious diseases

Dai JY, Hendrix CW, Richardson BA, Kelly C, Marzinke M, Chirenje ZM, Marrazzo JM, Brown ER

Factors associated with bone mineral density in healthy African women.

Archives of osteoporosis

Mgodi NM, Kelly C, Gati B, Greenspan S, Dai JY, Bragg V, Livant E, Piper JM, Nakabiito C, Magure T, Marrazzo JM, Chirenje ZM, Riddler SA, MTN-003B Protocol Team

Tenofovir-based preexposure prophylaxis for HIV infection among African women.

The New England journal of medicine

Marrazzo JM, Ramjee G, Richardson BA, Gomez K, Mgodi N, Nair G, Palanee T, Nakabiito C, van der Straten A, Noguchi L, Hendrix CW, Dai JY, Ganesh S, Mkhize B, Taljaard M, Parikh UM, Piper J, Mâsse B, Grossman C, Rooney J, Schwartz JL, Watts H, Marzinke MA, Hillier SL, McGowan IM, Chirenje ZM, VOICE Study Team

Hematological and biochemical laboratory reference intervals for Zimbabwean adolescents.

Clinical laboratory

Gomani P, Matubu AT, Mujuru HA, Munjoma MW, Tinago W, Mandozana G, Hakim JG, Gomo ZA, Chirenje ZM

Trends in the incidence of cancer in the black population of Harare, Zimbabwe 1991-2010.

International journal of cancer

Chokunonga E, Borok MZ, Chirenje ZM, Nyakabau AM, Parkin DM

Mucosal Escherichia coli bactericidal activity and immune mediators are associated with HIV-1 seroconversion in women participating in the HPTN 035 trial.

The Journal of infectious diseases

Dezzutti CS, Richardson BA, Marrazzo JM, Tugetman J, Ramjee G, Taha T, Chirenje ZM, Abdool Karim SS, Hillier SL, Herold BC, MTN Biomedical Sciences Working Group, HPTN 035 Protocol Team

Utility of colposcopy in a phase 2 portion of a microbicide clinical trial of BufferGel and 0.5% PRO 2000 Gel.

Journal of the International AIDS Society

Chirenje ZM, Mâsse BR, Maslankowski LA, Ramjee G, Coletti AS, Tembo TN, Magure TM, Soto-Torres L, Kelly C, Hillier S, Karim A

Safety and effectiveness of BufferGel and 0.5% PRO2000 gel for the prevention of HIV infection in women.

AIDS (London, England)

Abdool Karim SS, Richardson BA, Ramjee G, Hoffman IF, Chirenje ZM, Taha T, Kapina M, Maslankowski L, Coletti A, Profy A, Moench TR, Piwowar-Manning E, Mâsse B, Hillier SL, Soto-Torres L, HIV Prevention Trials Network (HPTN) 035 Study Team

Cancer survival in Harare, Zimbabwe, 1993-1997.

IARC scientific publications

Chokunonga E, Borok MZ, Chirenje ZM, Nyabakau AM, Parkin DM

Antiretroviral-based HIV prevention strategies for women.

Expert review of anti-infective therapy

Chirenje ZM, Marrazzo J, Parikh UM

Compliance and loss to follow up of HIV negative and positive mothers recruited from a PMTCT programme in Zimbabwe.

The Central African journal of medicine

Kurewa NE, Munjoma MM, Chirenje ZM, Rusakaniko S, Hussain A, Stray-Pedersen B

Acceptability of heat treating breast milk to prevent mother-to-child transmission of human immunodeficiency virus in Zimbabwe: a qualitative study.

Journal of human lactation : official journal of International Lactation Consultant Association

Israel-Ballard KA, Maternowska MC, Abrams BF, Morrison P, Chitibura L, Chipato T, Chirenje ZM, Padian NS, Chantry CJ

HIV and cancer of the cervix.

Best practice & research. Clinical obstetrics & gynaecology

Chirenje ZM

The CONRAD/WHO Update 2000 colposcopy manual: how well is it working?

Journal of acquired immune deficiency syndromes (1999)

Njoroge B, Chirenje ZM, Pandey B, Mirembe F, Joshi S, Low-Beer N, Maslankowski LA

Bacterial vaginosis and intravaginal practices: association with HIV.

The Central African journal of medicine

Mbizvo ME, Musya SE, Stray-Pedersen B, Chirenje Z, Hussain A

Situation analysis for cervical cancer diagnosis and treatment in east, central and southern African countries.

Bulletin of the World Health Organization

Chirenje ZM, Rusakaniko S, Kirumbi L, Ngwalle EW, Makuta-Tlebere P, Kaggwa S, Mpanju-Shumbusho W, Makoae L

Effect of HIV Disease in Treatment Outcome of Cervical Squamous Intraepithelial Lesions Among Zimbabwean Women.

Journal of lower genital tract disease

Chirenje ZM, Rusakaniko S, Akino V, Munjoma M, Mlingo M

Association of cervical SIL and HIV-1 infection among Zimbabwean women in an HIV/STI prevention study.

International journal of STD & AIDS

Chirenje ZM, Loeb L, Mwale M, Nyamapfeni P, Kamba M, Padian N

A randomised clinical trial of loop electrosurgical excision procedure (LEEP) versus cryotherapy in the treatment of cervical intraepithelial neoplasia.

Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology

Chirenje ZM, Rusakaniko S, Akino V, Mlingo M

Topical vaginal microbicides in HIV/STI prevention.

The Central African journal of medicine

Chirenje ZM

Determinants of reproductive tract infections among asymptomatic women in Harare, Zimbabwe.

The Central African journal of medicine

Mbizvo EM, Msuya SE, Stray-Pedersen B, Sundby J, Chirenje ZM, Hussain A

Situational analysis for diagnosis and treatment of cervical cancer in mainland Tanzania.

East African medical journal

Ngwalle EW, Mgaya HN, Mpanju-Shumbusho W, Chirenje ZM, Kirumbi L, Lebelle T, Kaggwa S

Adjunctive testing for cervical cancer in low resource settings with visual inspection, HPV, and the Pap smear.

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

Blumenthal PD, Gaffikin L, Chirenje ZM, McGrath J, Womack S, Shah K

Phase 1 trial of the topical microbicide BufferGel: safety results from four international sites.

Journal of acquired immune deficiency syndromes (1999)

van De Wijgert J, Fullem A, Kelly C, Mehendale S, Rugpao S, Kumwenda N, Chirenje Z, Joshi S, Taha T, Padian N, Bollinger R, Nelson K

The management of cervical intra-epithelial neoplasia.

The Central African journal of medicine

Chirenje Z

A review of cervical cancer patients presenting in Harare and Parirenyatwa Hospitals in 1998.

The Central African journal of medicine

Chirenje ZM, Rusakaniko S, Akino V, Mlingo M

Effect of intravaginal practices on the vaginal and cervical mucosa of Zimbabwean women.

Journal of acquired immune deficiency syndromes (1999)

van de Wijgert JH, Chirenje ZM, Iliff V, Mbizvo MT, Mason PR, Gwanzura L, Shiboski S, Padian NS

Intravaginal practices, vaginal flora disturbances, and acquisition of sexually transmitted diseases in Zimbabwean women.

The Journal of infectious diseases

van De Wijgert JH, Mason PR, Gwanzura L, Mbizvo MT, Chirenje ZM, Iliff V, Shiboski S, Padian NS

HPV-based cervical cancer screening in a population at high risk for HIV infection.

International journal of cancer

Womack SD, Chirenje ZM, Gaffikin L, Blumenthal PD, McGrath JA, Chipato T, Ngwalle S, Munjoma M, Shah KV

Evaluation of a human papillomavirus assay in cervical screening in Zimbabwe.

BJOG : an international journal of obstetrics and gynaecology

Womack SD, Chirenje ZM, Blumenthal PD, Gaffikin L, McGrath JA, Chipato T, Ngwalle E, Shah KV

Visual inspection of the cervix as a primary means of cervical cancer screening: results of a pilot study.

The Central African journal of medicine

Chirenje ZM, Chipato T, Kasule J, Rusakaniko S

Situation analysis for cervical cancer diagnosis and treatment in Zimbabwe.

The Central African journal of medicine

Chirenje ZM, Rusakaniko S, Chipato T, Mpanju-Shumbusho W, Ngwalle E, Kirumbi LW, Makuta-Tlebere P, Kaggwa S

Cervical cancer screening in a rural population of Zimbabwe.

The Central African journal of medicine

Thistle PJ, Chirenje ZM

Management of the patient with an abnormal Papanicolaou smear.

The Central African journal of medicine

Chirenje ZM

Screening for cervical cancer: experience from the Colposcopy Clinic at Harare Hospital.

The Central African journal of medicine

Chirenje ZM, Akino V