Pamela Murnane, PhD, MPH

ASST ADJ PROF-HCOMP
Epidemiology & Biostatistics
[email protected]

Pam Murnane is an Assistant Professor in the department of Epidemiology & Biostatistics at UCSF. Her research focusses on biological, behavioral, and structural factors that influence maternal and child health outcomes in the context of HIV in resource limited settings. She has expertise in adherence measurement and risk prediction, and is currently the PI of a K01 Award aiming to identify implementation strategies to deliver targeted adherence support for pregnant and postpartum women living with HIV in western Kenya.

Publications: 

Geographic Mobility and HIV Care Engagement among People Living with HIV in Rural Kenya and Uganda.

Tropical medicine and infectious disease

Ayieko J, Thorp M, Getahun M, Gandhi M, Maeri I, Gutin SA, Okiring J, Kamya MR, Bukusi EA, Charlebois ED, Petersen M, Havlir DV, Camlin CS, Murnane PM

First cases of SARS-CoV-2 infection and secondary transmission in Kisumu, Kenya.

PLOS global public health

Tippett Barr BA, Herman-Roloff A, Mburu M, Murnane PM, Sang N, Bukusi E, Oele E, Odhiambo A, Lewis-Kulzer J, Onyango CO, Hunsperger E, Odhiambo F, Joseph RH, Munyua P, Othieno K, Mulwa E, Akelo V, Muok E, Bulterys M, Nzioka C, Cohen CR

Analysis of Heavy Rainfall in Sub-Saharan Africa and HIV Transmission Risk, HIV Prevalence, and Sexually Transmitted Infections, 2005-2017.

JAMA network open

Nagata JM, Hampshire K, Epstein A, Lin F, Zakaras J, Murnane P, Charlebois ED, Tsai AC, Nash D, Weiser SD

Antiretroviral Therapy Adherence During and Postbreastfeeding Cessation Measured by Tenofovir Levels in Hair.

Journal of acquired immune deficiency syndromes (1999)

Nematadzira TG, Murnane PM, Odiase OJ, Bacchetti P, Okochi H, Tallerico R, Chanaiwa VM, Vhembo T, Mutambanengwe-Jacob MT, Louie A, Chipato T, Gandhi M, Stranix-Chibanda L, IMPAACT PROMISE Study Team

Distinct forms of migration and mobility are differentially associated with HIV treatment adherence.

AIDS (London, England)

Murnane PM, Gandhi M, Bacchetti P, Getahun M, Gutin SA, Okochi H, Maeri I, Eyul P, Omoding D, Okiring J, Tallerico R, Louie A, Akullian A, Kamya MR, Bukusi EA, Charlebois ED, Camlin CS

Disclosure to South African children about their own HIV status over time.

AIDS care

Wu M, Shiau S, Strehlau R, Liberty A, Patel F, Burke M, Murnane PM, Violari A, Yin MT, Abrams EJ, Kuhn L, Arpadi S

Machine Learning Algorithms Using Routinely Collected Data Do Not Adequately Predict Viremia to Inform Targeted Services in Postpartum Women Living With HIV.

Journal of acquired immune deficiency syndromes (1999)

Murnane PM, Ayieko J, Vittinghoff E, Gandhi M, Katumbi C, Milala B, Nakaye C, Kanda P, Moodley D, Nyati ME, Loftis AJ, Fowler MG, Flynn P, Currier JS, Cohen CR

Performance-Enhancing Substance Use and Sexual Risk Behaviors among U.S. Men: Results from a Prospective Cohort Study.

Journal of sex research

Ganson KT, Jackson DB, Testa A, Murnane PM, Nagata JM

Factors associated with phosphatidylethanol (PEth) sensitivity for detecting unhealthy alcohol use: An individual patient data meta-analysis.

Alcoholism, clinical and experimental research

Hahn JA, Murnane PM, Vittinghoff E, Muyindike WR, Emenyonu NI, Fatch R, Chamie G, Haberer JE, Francis JM, Kapiga S, Jacobson K, Myers B, Couture MC, DiClemente RJ, Brown JL, So-Armah K, Sulkowski M, Marcus GM, Woolf-King S, Cook RL, Richards VL, Molina P, Ferguson T, Welsh D, Piano MR, Phillips SA, Stewart S, Afshar M, Page K, McGinnis K, Fiellin DA, Justice AC, Bryant K, Saitz R

Perinatal Food Insecurity and Postpartum Psychosocial Stress are Positively Associated Among Kenyan Women of Mixed HIV Status.

AIDS and behavior

Murnane PM, Miller JD, Tuthill EL, Collins SM, Neilands TB, Onono M, Cohen CR, Weiser SD, Laudenslager ML, Young SL

Short- and Long-Term Pharmacologic Measures of HIV Pre-exposure Prophylaxis Use Among High-Risk Men Who Have Sex With Men in HPTN 067/ADAPT.

Journal of acquired immune deficiency syndromes (1999)

Velloza J, Bacchetti P, Hendrix CW, Murnane P, Hughes JP, Li M, Curlin ME, Holtz TH, Mannheimer S, Marzinke MA, Amico KR, Liu A, Piwowar-Manning E, Eshleman SH, Dye BJ, Gandhi M, Grant RM, HPTN 067/ADAPT Study Team

Tenofovir concentrations in hair strongly predict virologic suppression in breastfeeding women.

AIDS (London, England)

Murnane PM, Bacchetti P, Currier JS, Brummel S, Okochi H, Phung N, Louie A, Kuncze K, Hoffman RM, Nematadzira T, Soko DK, Owor M, Saidi F, Flynn PM, Fowler MG, Gandhi M

Research priorities to inform "Treat All" policy implementation for people living with HIV in sub-Saharan Africa: a consensus statement from the International epidemiology Databases to Evaluate AIDS (IeDEA).

Journal of the International AIDS Society

Yotebieng M, Brazier E, Addison D, Kimmel AD, Cornell M, Keiser O, Parcesepe AM, Onovo A, Lancaster KE, Castelnuovo B, Murnane PM, Cohen CR, Vreeman RC, Davies MA, Duda SN, Yiannoutsos CT, Bono RS, Agler R, Bernard C, Syvertsen JL, Sinayobye JD, Wikramanayake R, Sohn AH, von Groote PM, Wandeler G, Leroy V, Williams CF, Wools-Kaloustian K, Nash D, IeDEA Treat All in sub-Saharan Africa Consensus Statement Working Group

Achieving UNAIDS 90-90-90 targets for pregnant and postpartum women in sub-Saharan Africa: progress, gaps and research needs.

Journal of virus eradication

Abuogi LL, Humphrey JM, Mpody C, Yotebieng M, Murnane PM, Clouse K, Otieno L, Cohen CR, Wools-Kaloustian K

12-month outcomes of HIV-infected infants identified at birth at one maternity site in Johannesburg, South Africa: an observational cohort study.

The lancet. HIV

Technau KG, Strehlau R, Patel F, Shiau S, Burke M, Conradie M, Sorour G, Sherman GG, Coovadia A, Murnane PM, Abrams EJ, Kuhn L

Reply to Van de Wijer et al.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Murnane PM, Strehlau R, Shiau S, Patel F, Mbete N, Hunt G, Abrams EJ, Coovadia A, Kuhn L

Modeling HIV disease progression and transmission at population-level: The potential impact of modifying disease progression in HIV treatment programs.

Epidemics

Ross JM, Ying R, Celum CL, Baeten JM, Thomas KK, Murnane PM, van Rooyen H, Hughes JP, Barnabas RV

Hair levels of preexposure prophylaxis drugs measure adherence and are associated with renal decline among men/transwomen.

AIDS (London, England)

Gandhi M, Murnane PM, Bacchetti P, Elion R, Kolber MA, Cohen SE, Horng H, Louie A, Kuncze K, Koss CA, Anderson PL, Buchbinder S, Liu A

Prevalence and outcomes of HIV-1 diagnostic challenges during universal birth testing - an urban South African observational cohort.

Journal of the International AIDS Society

Technau KG, Mazanderani AH, Kuhn L, Hans L, Strehlau R, Abrams EJ, Conradie M, Coovadia A, Mbete N, Murnane PM, Patel F, Shiau S, Tiemessen CT, Sherman GG

Switching to Efavirenz Versus Remaining on Ritonavir-boosted Lopinavir in Human Immunodeficiency Virus-infected Children Exposed to Nevirapine: Long-term Outcomes of a Randomized Trial.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Murnane PM, Strehlau R, Shiau S, Patel F, Mbete N, Hunt G, Abrams EJ, Coovadia A, Kuhn L

Extent of disclosure: what perinatally HIV-infected children have been told about their own HIV status.

AIDS care

Murnane PM, Sigamoney SL, Pinillos F, Shiau S, Strehlau R, Patel F, Liberty A, Abrams EJ, Arpadi S, Coovadia A, Violari A, Kuhn L

Regulatory T-Cell Activity But Not Conventional HIV-Specific T-Cell Responses Are Associated With Protection From HIV-1 Infection.

Journal of acquired immune deficiency syndromes (1999)

Pattacini L, Baeten JM, Thomas KK, Fluharty TR, Murnane PM, Donnell D, Bukusi E, Ronald A, Mugo N, Lingappa JR, Celum C, McElrath MJ, Lund JM, Partners PrEP Study Team

Estimating efficacy in a randomized trial with product nonadherence: application of multiple methods to a trial of preexposure prophylaxis for HIV prevention.

American journal of epidemiology

Murnane PM, Brown ER, Donnell D, Coley RY, Mugo N, Mujugira A, Celum C, Baeten JM, Partners PrEP Study Team

Murnane, Coley, and Baeten respond to "every good randomization deserves observation".

American journal of epidemiology

Murnane PM, Coley RY, Baeten JM

Estimating PMTCT's Impact on Heterosexual HIV Transmission: A Mathematical Modeling Analysis.

PloS one

Khanna AS, Roberts ST, Cassels S, Ying R, John-Stewart G, Goodreau SM, Baeten JM, Murnane PM, Celum C, Barnabas RV

Antiretroviral Pre-Exposure Prophylaxis Does Not Enhance Immune Responses to HIV in Exposed but Uninfected Persons.

The Journal of infectious diseases

Pattacini L, Murnane PM, Baeten JM, Fluharty TR, Thomas KK, Bukusi E, Katabira E, Mugo N, Donnell D, Lingappa JR, Celum C, Marzinke M, McElrath MJ, Lund JM, Partners PrEP Study Team

Initiation of antiretroviral therapy and viral suppression after home HIV testing and counselling in KwaZulu-Natal, South Africa, and Mbarara district, Uganda: a prospective, observational intervention study.

The lancet. HIV

Barnabas RV, van Rooyen H, Tumwesigye E, Murnane PM, Baeten JM, Humphries H, Turyamureeba B, Joseph P, Krows M, Hughes JP, Celum C

Pre-exposure prophylaxis for HIV-1 prevention does not diminish the pregnancy prevention effectiveness of hormonal contraception.

AIDS (London, England)

Murnane PM, Heffron R, Ronald A, Bukusi EA, Donnell D, Mugo NR, Were E, Mujugira A, Kiarie J, Celum C, Baeten JM, Partners PrEP Study Team

Enhanced and efficient detection of virus-driven cytokine expression by human NK and T cells.

Journal of virological methods

Pattacini L, Murnane PM, Fluharty TR, Katabira E, De Rosa SC, Baeten JM, Lund JM

High HIV testing uptake and linkage to care in a novel program of home-based HIV counseling and testing with facilitated referral in KwaZulu-Natal, South Africa.

Journal of acquired immune deficiency syndromes (1999)

van Rooyen H, Barnabas RV, Baeten JM, Phakathi Z, Joseph P, Krows M, Hong T, Murnane PM, Hughes J, Celum C

Efficacy of preexposure prophylaxis for HIV-1 prevention among high-risk heterosexuals: subgroup analyses from a randomized trial.

AIDS (London, England)

Murnane PM, Celum C, Mugo N, Campbell JD, Donnell D, Bukusi E, Mujugira A, Tappero J, Kahle EM, Thomas KK, Baeten JM, Partners PrEP Study Team

Differential regulatory T cell activity in HIV type 1-exposed seronegative individuals.

AIDS research and human retroviruses

Pattacini L, Murnane PM, Kahle EM, Bolton MJ, Delrow JJ, Lingappa JR, Katabira E, Donnell D, McElrath MJ, Baeten JM, Lund JM

Household-based HIV counseling and testing as a platform for referral to HIV care and medical male circumcision in Uganda: a pilot evaluation.

PloS one

Tumwebaze H, Tumwesigye E, Baeten JM, Kurth AE, Revall J, Murnane PM, Chang LW, Celum C

Using plasma viral load to guide antiretroviral therapy initiation to prevent HIV-1 transmission.

PloS one

Murnane PM, Hughes JP, Celum C, Lingappa JR, Mugo N, Farquhar C, Kiarie J, Wald A, Baeten JM, Partners in Prevention HSV/HIV Transmission Study Team

Lactation-associated postpartum weight changes among HIV-infected women in Zambia.

International journal of epidemiology

Murnane PM, Arpadi SM, Sinkala M, Kankasa C, Mwiya M, Kasonde P, Thea DM, Aldrovandi GM, Kuhn L

Behavioral influences on preterm birth: a review.

Epidemiology (Cambridge, Mass.)

Savitz DA, Murnane P

Role: 
Investigators