Joelle Brown, PhD

Associate Adjunct Professor
Epidemiology & Biostatistics
[email protected]
+1 415 476-5866
Publications: 

Type 1 Human Immunodeficiency Virus (HIV-1) Incidence, Adherence, and Drug Resistance in Individuals Taking Daily Emtricitabine/Tenofovir Disoproxil Fumarate for HIV-1 Pre-exposure Prophylaxis: Pooled Analysis From 72 Global Studies.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Landovitz RJ, Tao L, Yang J, de Boer M, Carter C, Das M, Baeten JM, Liu A, Hoover KW, Celum C, Grinsztejn B, Morris S, Wheeler DP, Mayer KH, Golub SA, Bekker LG, Diabaté S, Hoornenborg E, Myers J, Leech AA, McCormack S, Chan PA, Sweat M, Matthews LT, Grant R, Global F/TDF PrEP Study Team

"We chose PrEP because I wanted to be sure that this child my wife was going to conceive was indeed mine." Factors influencing the choice of safer conception methods and experiences with its use: a qualitative study among HIV sero-discordant couples in Zi

BMC public health

Brown JM, Musara P, Gitome S, Chitukuta M, Mataveke B, Chirenda T, Mgodi N, Mutero P, Matubu A, Chareka G, Chasakara C, Murombedzi C, Makurumure T, Hughes CS, Bukusi E, Cohen CR, Shiboski S, Darbes L, Rutherford GW, Chirenje ZM, Mhlanga F

"First was to sit down and bring our minds together". A qualitative study on safer conception decision-making among HIV sero-different couples in Zimbabwe.

Sexual and reproductive health matters

Gitome S, Musara P, Chitukuta M, Mhlanga F, Mateveke B, Chirenda T, Mgodi N, Mutero P, Matubu A, Chareka G, Chasakara C, Murombedzi C, Makurumure T, Smith-Hughes C, Bukusi E, Cohen CR, Shiboski S, Darbes L, Rutherford GW, Chirenje ZM, Brown JM

Population pharmacokinetics of primaquine and its metabolites in African males.

Malaria journal

Chotsiri P, Mahamar A, Diawara H, Fasinu PS, Diarra K, Sanogo K, Bousema T, Walker LA, Brown JM, Dicko A, Gosling R, Chen I, Tarning J

Advancing the use of Long-Acting Extended Delivery formulations for HIV prevention in sub-Saharan Africa: challenges, opportunities, and recommendations.

Journal of the International AIDS Society

Mgodi NM, Murewanhema G, Moyo E, Samba C, Musuka G, Dzinamarira T, Brown JM

Preventing HIV and achieving pregnancy among HIV sero-different couples: Pilot study of a safer conception intervention in Zimbabwe.

PLOS global public health

Brown JM, Gitome S, Mataveke B, Chirenda T, Matubu A, Chareka G, Chasakara C, Mgodi N, Murombedzi C, Musara P, Makurumure T, Hughes CS, Bukusi E, Cohen CR, Shiboski S, Darbes L, Kahn JG, Rutherford GW, Chirenje ZM, Mhlanga F

Safety of single-dose primaquine as a Plasmodium falciparum gametocytocide: a systematic review and meta-analysis of individual patient data.

BMC medicine

Stepniewska K, Allen EN, Humphreys GS, Poirot E, Craig E, Kennon K, Yilma D, Bousema T, Guerin PJ, White NJ, Price RN, Raman J, Martensson A, Mwaiswelo RO, Bancone G, Bastiaens GJH, Bjorkman A, Brown JM, D'Alessandro U, Dicko AA, El-Sayed B, Elzaki SE, Eziefula AC, Gonçalves BP, Hamid MMA, Kaneko A, Kariuki S, Khan W, Kwambai TK, Ley B, Ngasala BE, Nosten F, Okebe J, Samuels AM, Smit MR, Stone WJR, Sutanto I, Ter Kuile F, Tine RC, Tiono AB, Drakeley CJ, Gosling R, Stergachis A, Barnes KI, Chen I

Efficacy of Single-Dose Primaquine With Artemisinin Combination Therapy on Plasmodium falciparum Gametocytes and Transmission: An Individual Patient Meta-Analysis.

The Journal of infectious diseases

Stepniewska K, Humphreys GS, Gonçalves BP, Craig E, Gosling R, Guerin PJ, Price RN, Barnes KI, Raman J, Smit MR, D'Alessandro U, Stone WJR, Bjorkman A, Samuels AM, Arroyo-Arroyo MI, Bastiaens GJH, Brown JM, Dicko A, El-Sayed BB, Elzaki SG, Eziefula AC, Kariuki S, Kwambai TK, Maestre AE, Martensson A, Mosha D, Mwaiswelo RO, Ngasala BE, Okebe J, Roh ME, Sawa P, Tiono AB, Chen I, Drakeley CJ, Bousema T

Mechanistic Modeling of Primaquine Pharmacokinetics, Gametocytocidal Activity, and Mosquito Infectivity.

Clinical pharmacology and therapeutics

Chotsiri P, Mahamar A, Hoglund RM, Koita F, Sanogo K, Diawara H, Dicko A, Simpson JA, Bousema T, White NJ, Brown JM, Gosling R, Chen I, Tarning J

Estimated costs for the delivery of safer conception strategies for HIV-discordant couples in Zimbabwe: a cost analysis.

BMC health services research

Hughes CS, Brown J, Murombedzi C, Chirenda T, Chareka G, Mhlanga F, Mateveke B, Gitome S, Makurumure T, Matubu A, Mgodi N, Chirenje Z, Kahn JG

Safety of Single-Dose Primaquine in G6PD-Deficient and G6PD-Normal Males in Mali Without Malaria: An Open-Label, Phase 1, Dose-Adjustment Trial.

The Journal of infectious diseases

Chen I, Diawara H, Mahamar A, Sanogo K, Keita S, Kone D, Diarra K, Djimde M, Keita M, Brown J, Roh ME, Hwang J, Pett H, Murphy M, Niemi M, Greenhouse B, Bousema T, Gosling R, Dicko A

Efficacy and safety of primaquine and methylene blue for prevention of Plasmodium falciparum transmission in Mali: a phase 2, single-blind, randomised controlled trial.

The Lancet. Infectious diseases

Dicko A, Roh ME, Diawara H, Mahamar A, Soumare HM, Lanke K, Bradley J, Sanogo K, Kone DT, Diarra K, Keita S, Issiaka D, Traore SF, McCulloch C, Stone WJR, Hwang J, Müller O, Brown JM, Srinivasan V, Drakeley C, Gosling R, Chen I, Bousema T

What motivates serodiscordant couples to prevent HIV transmission within their relationships: findings from a PrEP implementation study in Kenya

Culture, Health, and Sexuality

Patel RC, Leddy AM, Odoyo J, Anand K, Stanford-Moore G, Wakhungu I, Bukusi EA, Baeten JM, Brown JM

A Molecular Assay to Quantify Male and Female Plasmodium falciparum Gametocytes: Results From 2 Randomized Controlled Trials Using Primaquine for Gametocyte Clearance.

The Journal of infectious diseases

Stone W, Sawa P, Lanke K, Rijpma S, Oriango R, Nyaurah M, Osodo P, Osoti V, Mahamar A, Diawara H, Woestenenk R, Graumans W, van de Vegte-Bolmer M, Bradley J, Chen I, Brown J, Siciliano G, Alano P, Gosling R, Dicko A, Drakeley C, Bousema T

"Since both of us are using antiretrovirals, we have been supportive to each other": facilitators and barriers of pre-exposure prophylaxis use in heterosexual HIV serodiscordant couples in Kisumu, Kenya.

Journal of the International AIDS Society

Patel RC, Stanford-Moore G, Odoyo J, Pyra M, Wakhungu I, Anand K, Bukusi EA, Baeten JM, Brown JM

A Novel Safer Conception Counseling Toolkit for the Prevention of HIV: A Mixed-Methods Evaluation in Kisumu, Kenya.

AIDS education and prevention : official publication of the International Society for AIDS Education

Brown J, Njoroge B, Akama E, Breitnauer B, Leddy A, Darbes L, Omondi R, Mmeje O

Comparison of molecular quantification of Plasmodium falciparum gametocytes by Pfs25 qRT-PCR and QT-NASBA in relation to mosquito infectivity.

Malaria journal

Pett H, Gonçalves BP, Dicko A, Nébié I, Tiono AB, Lanke K, Bradley J, Chen I, Diawara H, Mahamar A, Soumare HM, Traore SF, Baber I, Sirima SB, Sauerwein R, Brown J, Gosling R, Felger I, Drakeley C, Bousema T

Development of a pharmacovigilance safety monitoring tool for the rollout of single low-dose primaquine and artemether-lumefantrine to treat Plasmodium falciparum infections in Swaziland: a pilot study.

Malaria journal

Poirot E, Soble A, Ntshalintshali N, Mwandemele A, Mkhonta N, Malambe C, Vilakati S, Pan S, Darteh S, Maphalala G, Brown J, Hwang J, Pace C, Stergachis A, Vittinghoff E, Kunene S, Gosling R

Motivations for Intravaginal Product Use among a Cohort of Women in Los Angeles.

PloS one

Brown JM, Poirot E, Hess KL, Brown S, Vertucci M, Hezareh M

Primaquine to reduce transmission of Plasmodium falciparum malaria in Mali: a single-blind, dose-ranging, adaptive randomised phase 2 trial.

The Lancet. Infectious diseases

Dicko A, Brown JM, Diawara H, Baber I, Mahamar A, Soumare HM, Sanogo K, Koita F, Keita S, Traore SF, Chen I, Poirot E, Hwang J, McCulloch C, Lanke K, Pett H, Niemi M, Nosten F, Bousema T, Gosling R

Community perceptions of childbearing and use of safer conception strategies among HIV-discordant couples in Kisumu, Kenya.

Journal of the International AIDS Society

Breitnauer BT, Mmeje O, Njoroge B, Darbes LA, Leddy A, Brown J

Hormonal contraception and the risk of HIV acquisition: an individual participant data meta-analysis.

PLoS medicine

Morrison CS, Chen PL, Kwok C, Baeten JM, Brown J, Crook AM, Van Damme L, Delany-Moretlwe S, Francis SC, Friedland BA, Hayes RJ, Heffron R, Kapiga S, Karim QA, Karpoff S, Kaul R, McClelland RS, McCormack S, McGrath N, Myer L, Rees H, van der Straten A, Watson-Jones D, van de Wijgert JH, Stalter R, Low N

The independent effect of living in malaria hotspots on future malaria infection: an observational study from Misungwi, Tanzania.

Malaria journal

Mosha JF, Sturrock HJ, Brown JM, Hashim R, Kibiki G, Chandramohan D, Gosling RD

A comparison of two measures of HIV diversity in multi-assay algorithms for HIV incidence estimation.

PloS one

Cousins MM, Konikoff J, Sabin D, Khaki L, Longosz AF, Laeyendecker O, Celum C, Buchbinder SP, Seage GR, Kirk GD, Moore RD, Mehta SH, Margolick JB, Brown J, Mayer KH, Kobin BA, Wheeler D, Justman JE, Hodder SL, Quinn TC, Brookmeyer R, Eshleman SH

Incorrect identification of recent HIV infection in adults in the United States using a limiting-antigen avidity assay.

AIDS (London, England)

Longosz AF, Mehta SH, Kirk GD, Margolick JB, Brown J, Quinn TC, Eshleman SH, Laeyendecker O

Hot spot or not: a comparison of spatial statistical methods to predict prospective malaria infections.

Malaria journal

Mosha JF, Sturrock HJ, Greenwood B, Sutherland CJ, Gadalla NB, Atwal S, Hemelaar S, Brown JM, Drakeley C, Kibiki G, Bousema T, Chandramohan D, Gosling RD

Performance of a limiting-antigen avidity enzyme immunoassay for cross-sectional estimation of HIV incidence in the United States.

PloS one

Konikoff J, Brookmeyer R, Longosz AF, Cousins MM, Celum C, Buchbinder SP, Seage GR, Kirk GD, Moore RD, Mehta SH, Margolick JB, Brown J, Mayer KH, Koblin BA, Justman JE, Hodder SL, Quinn TC, Eshleman SH, Laeyendecker O

Impact of malaria and helminth infections on immunogenicity of the human papillomavirus-16/18 AS04-adjuvanted vaccine in Tanzania.

Vaccine

Brown J, Baisley K, Kavishe B, Changalucha J, Andreasen A, Mayaud P, Gumodoka B, Kapiga S, Hayes R, Watson-Jones D

HIV diversity as a biomarker for HIV incidence estimation: including a high-resolution melting diversity assay in a multiassay algorithm.

Journal of clinical microbiology

Cousins MM, Konikoff J, Laeyendecker O, Celum C, Buchbinder SP, Seage GR, Kirk GD, Moore RD, Mehta SH, Margolick JB, Brown J, Mayer KH, Koblin BA, Wheeler D, Justman JE, Hodder SL, Quinn TC, Brookmeyer R, Eshleman SH

Intravaginal practices and risk of bacterial vaginosis and candidiasis infection among a cohort of women in the United States.

Obstetrics and gynecology

Brown JM, Hess KL, Brown S, Murphy C, Waldman AL, Hezareh M

High prevalence and incidence of human papillomavirus in a cohort of healthy young African female subjects.

Sexually transmitted infections

Watson-Jones D, Baisley K, Brown J, Kavishe B, Andreasen A, Changalucha J, Mayaud P, Kapiga S, Gumodoka B, Hayes RJ, de Sanjosé S

Acceptability of potential rectal microbicide delivery systems for HIV prevention: a randomized crossover trial.

AIDS and behavior

Pines HA, Gorbach PM, Weiss RE, Hess K, Murphy R, Saunders T, Brown J, Anton PA, Cranston RD

Intimate partner violence and anal intercourse in young adult heterosexual relationships.

Perspectives on sexual and reproductive health

Hess KL, Javanbakht M, Brown JM, Weiss RE, Hsu P, Gorbach PM

Safety and immunogenicity of human papillomavirus-16/18 AS04-adjuvanted vaccine: a randomized trial in 10-25-year-old HIV-Seronegative African girls and young women.

The Journal of infectious diseases

Sow PS, Watson-Jones D, Kiviat N, Changalucha J, Mbaye KD, Brown J, Bousso K, Kavishe B, Andreasen A, Toure M, Kapiga S, Mayaud P, Hayes R, Lebacq M, Herazeh M, Thomas F, Descamps D

HIV incidence determination in the United States: a multiassay approach.

The Journal of infectious diseases

Laeyendecker O, Brookmeyer R, Cousins MM, Mullis CE, Konikoff J, Donnell D, Celum C, Buchbinder SP, Seage GR, Kirk GD, Mehta SH, Astemborski J, Jacobson LP, Margolick JB, Brown J, Quinn TC, Eshleman SH

Genital Herpes. In "Women and Health" (Goldman and Thompson Eds), Academic Press, California

Genital Herpes. In "Women and Health" (Goldman and Thompson Eds), Academic Press, California

Perti T, Brown JM, Wald A

Trypan blue staining to determine vaginal exposure in two types of plastic vaginal applicators containing two different microbicide formulations.

Sexually transmitted diseases

Hemmerling A, Harrison WG, Brown JM, Moscicki B, Oziemkowska M, Bukusi EA, Cohen CR

HPV Type Distribution and Cervical Cytology among HIV-Positive Tanzanian and South African Women.

ISRN obstetrics and gynecology

Dols JA, Reid G, Brown JM, Tempelman H, Bontekoe TR, Quint WG, Boon ME

Intimate partner violence and sexually transmitted infections among young adult women.

Sexually transmitted diseases

Hess KL, Javanbakht M, Brown JM, Weiss RE, Hsu P, Gorbach PM

Genital Herpes

In “Women and Health” (Goldman and Thompson Eds), Academic Press

Perti T, Brown JM, Wald A

Factors associated with incorrect identification of recent HIV infection using the BED capture immunoassay.

AIDS research and human retroviruses

Laeyendecker O, Brookmeyer R, Oliver AE, Mullis CE, Eaton KP, Mueller AC, Jacobson LP, Margolick JB, Brown J, Rinaldo CR, Quinn TC, Eshleman SH, Multicenter Aids Cohort Study Macs

Intravaginal practices, bacterial vaginosis, and HIV infection in women: individual participant data meta-analysis.

PLoS medicine

Low N, Chersich MF, Schmidlin K, Egger M, Francis SC, van de Wijgert JH, Hayes RJ, Baeten JM, Brown J, Delany-Moretlwe S, Kaul R, McGrath N, Morrison C, Myer L, Temmerman M, van der Straten A, Watson-Jones D, Zwahlen M, Hilber AM

Increased levels of immune activation in the genital tract of healthy young women from sub-Saharan Africa.

AIDS (London, England)

Cohen CR, Moscicki AB, Scott ME, Ma Y, Shiboski S, Bukusi E, Daud I, Rebbapragada A, Brown J, Kaul R

Disentangling contributions of reproductive tract infections to HIV acquisition in African Women.

Sexually transmitted diseases

van de Wijgert JH, Morrison CS, Brown J, Kwok C, Van Der Pol B, Chipato T, Byamugisha JK, Padian N, Salata RA

Microbicide safety and effectiveness: an overview of recent clinical trials

Current opinion in HIV and AIDS

Brown JM, Poynten M, Sovero M, Millwood IY, Kaldor J

Microbicide safety and effectiveness: an overview of recent clinical trials.

Current opinion in HIV and AIDS

Poynten M, Brown JM, Sovero M, Millwood IY, Kaldor JM

Incident and prevalent herpes simplex virus type 2 infection increases risk of HIV acquisition among women in Uganda and Zimbabwe.

AIDS (London, England)

Brown JM, Wald A, Hubbard A, Rungruengthanakit K, Chipato T, Rugpao S, Mmiro F, Celentano DD, Salata RS, Morrison CS, Richardson BA, Padian NS

Hormonal contraception and the risk of HIV acquisition.

AIDS (London, England)

Morrison CS, Richardson BA, Mmiro F, Chipato T, Celentano DD, Luoto J, Mugerwa R, Padian N, Rugpao S, Brown JM, Cornelisse P, Salata RA, Hormonal Contraception and the Risk of HIV Acquisition (HC-HIV) Study Group

HIV incidence among women of reproductive age in Malawi and Zimbabwe.

Sexually transmitted diseases

Kumwenda N, Hoffman I, Chirenje M, Kelly C, Coletti A, Ristow A, Martinson F, Brown J, Chilongozi D, Richardson B, Rosenberg Z, Padian N, Taha T

How are condoms used in a family planning setting: evidence from Zimbabwe

Centr. Afr. J. Med

Magwali TL, Steiner MJ, Toms H, Brown JM

Nonoxynol-9 100 mg gel: multi-site safety study from sub-Saharan Africa.

AIDS (London, England)

Hoffman IF, Taha TE, Padian NS, Kelly CW, Welch JD, Martinson FE, Kumwenda NI, Rosenberg ZF, Chilongozi DA, Brown JM, Chirenje M, Richardson BA

Genital Herpes

In “Women and Health” (Goldman and Thompson Eds), Academic Press.

Wald A, Brown JM

Role: 
Investigators