Zvavahera (Mike) Chirenje, MD, FRCOG

Professor, Department of Obstetrics, Gynecology & Reproductive Sciences
Professor, College of Health Sciences, University of Zimbabwe
 

Dr. Chirenje is an attending Gynecological Oncologist at Parirenyatwa Hospital in Harare, Zimbabwe. He also conducts HIV prevention clinical trials for women with a particular emphasis on microbicide and pre-exposure prophlyaxis (PrEP) development.

In 1994, Dr. Chirenje was one of the founding members of the University of Zimbabwe - University of California, San Francisco (UZ-UCSF) Collaborative Research Programme in Women’s Health, and has served as the Executive Director since 2002. He provides fiscal, operational, and scientific oversight of a complex research unit that employs about 300 staff and research investigators. He serves as Principal Investigator for a large National Institutes of Health-sponsored UZ-UCSF Clinical Trials Unit (CTU), providing leadership that promotes high quality research for the four affiliated Division of AIDS-funded HIV/AIDS networks of ACTG, HPTN, IMPAACT, and MTN. His site was awarded HIV vaccine research status in 2014 (HVTN).

Dr. Chirenje was Principal Investigator for a large protocol that screened 11,000 women in Harare, which became an international milestone study demonstrating the effectiveness of visual inspection with acetic acid (VIA) in screening for cervical cancer in low resource settings. He is chairman of the cervical cancer control program in Zimbabwe. For the last 25 years, Dr. Chirenje has been Director for the UZ - UCSF Dysplasia Clinic at Spilhaus Clinical Research Site in Harare, where he has introduced digital colposcopy, loop excision treatment and cyrotherapy training syllabus for VIA workshops. He is chair of the Mentored Research Scholarship Program at the University of Zimbabwe.

 

Areas of interest:

  • Cervical Cancer screening and treatment of pre-cancer lesions in low resource settings
  • Natural history of human papillomavirus (HPV) in HIV-infected and uninfected women
  • Association of HIV with cervical and vulval cancer
  • Microbicides development for HIV prevention in women
  • Antiretroviral-based clinical trials for PrEP HIV prevention in women

 

Publications: 
  1. Antenatal depression: Associations with birth and neonatal outcomes among women attending maternity care in Harare, Zimbabwe. PLoS One. 2023; 18(7):e0270873. Kaiyo-Utete M, Langhaug L, Chingono A, Dambi JM, Magwali T, Henderson C, Chirenje ZM. PMID: 37418441; PMCID: PMC10328234.
    View in: PubMed   Mentions:    Fields:    Translation:Humans
  2. Strategic actions to advance multipurpose prevention technologies in low- and middle-income countries. Front Reprod Health. 2023; 5:1150857. Young Holt B, van der Straten A, Barker T, Chirenje ZM, Cameron AI, Scott C, Casas CP, Romano J. PMID: 37465533; PMCID: PMC10351869.
    View in: PubMed   Mentions:
  3. Population-Level Correlation Between Incidence of Curable Sexually Transmitted Infections and Human Immunodeficiency Virus (HIV)-1 Among African Women Participating in HIV-1 Pre-Exposure Prophylaxis Trials. J Infect Dis. 2022 09 21; 226(6):1069-1074. Hunidzarira P, Brown ER, Chirenje ZM, Hillier SL, Marrazzo JM, Palanee-Phillips T, Kiweewa FM, Baeten JM, MTN-003/VOICE and MTN-020/ASPIRE Study Teams. PMID: 35763413; PMCID: PMC10233491.
    View in: PubMed   Mentions:    Fields:    Translation:HumansCellsPHPublic Health
  4. Alignment of PrEP adherence with periods of HIV risk among adolescent girls and young women in South Africa and Zimbabwe: a secondary analysis of the HPTN 082 randomised controlled trial. Lancet HIV. 2022 10; 9(10):e680-e689. Velloza J, Donnell D, Hosek S, Anderson PL, Chirenje ZM, Mgodi N, Bekker LG, Marzinke MA, Delany-Moretlwe S, Celum C. PMID: 36087612; PMCID: PMC9530001.
    View in: PubMed   Mentions: 5     Fields:    Translation:HumansPHPublic Health
  5. Understanding the public health value and defining preferred product characteristics for therapeutic human papillomavirus (HPV) vaccines: World Health Organization consultations, October 2021-March 2022. Vaccine. 2022 09 29; 40(41):5843-5855. Prudden HJ, Achilles SL, Schocken C, Broutet N, Canfell K, Akaba H, Basu P, Bhatla N, Chirenje ZM, Delany-Moretlwe S, Denny L, Gamage DG, Herrero R, Hutubessy R, Villa LL, Murillo R, Schiller JT, Stanley M, Temmerman M, Zhao F, Ogilvie G, Kaslow DC, Dull P, Gottlieb SL, Therapeutic HPV Vaccine PPC Expert Consultation Group*. PMID: 36008233.
    View in: PubMed   Mentions: 2     Fields:    Translation:HumansCellsPHPublic Health
  6. Patient experiences of living with cancer before interaction with palliative care services in Zimbabwe: A qualitative secondary data analysis. Eur J Cancer Care (Engl). 2022 Sep; 31(5):e13632. Dandadzi A, Chapman E, Chirenje ZM, Namukwaya E, Pini S, Nkhoma K, Allsop MJ. PMID: 35712980; PMCID: PMC9542205.
    View in: PubMed   Mentions: 1     Fields:    Translation:Humans
  7. Impact of catch-up human papillomavirus vaccination on cervical cancer incidence in Kenya: A mathematical modeling evaluation of HPV vaccination strategies in the context of moderate HIV prevalence. EClinicalMedicine. 2022 Mar; 45:101306. Liu G, Mugo NR, Bayer C, Rao DW, Onono M, Mgodi NM, Chirenje ZM, Njoroge BW, Tan N, Bukusi EA, Barnabas RV. PMID: 35243272; PMCID: PMC8860915.
    View in: PubMed   Mentions: 5  
  8. Prevalent human papillomavirus infection increases the risk of HIV acquisition in African women: advancing the argument for human papillomavirus immunization. AIDS. 2022 02 01; 36(2):257-265. Liu G, Mugo NR, Brown ER, Mgodi NM, Chirenje ZM, Marrazzo JM, Winer RL, Mansoor L, Palanee-Phillips T, Siva SS, Naidoo L, Jeenarain N, Gaffoor Z, Nair GL, Selepe P, Nakabiito C, Mkhize B, Mirembe BG, Taljaard M, Panchia R, Baeten JM, Balkus JE, Hladik F, Celum CL, Barnabas RV. PMID: 34172672; PMCID: PMC8702475.
    View in: PubMed   Mentions: 2     Fields:    Translation:HumansCellsPHPublic Health
  9. The IARC Perspective on Cervical Cancer Screening. N Engl J Med. 2021 11 11; 385(20):1908-1918. Bouvard V, Wentzensen N, Mackie A, Berkhof J, Brotherton J, Giorgi-Rossi P, Kupets R, Smith R, Arrossi S, Bendahhou K, Canfell K, Chirenje ZM, Chung MH, Del Pino M, de Sanjosé S, Elfström M, Franco EL, Hamashima C, Hamers FF, Herrington CS, Murillo R, Sangrajrang S, Sankaranarayanan R, Saraiya M, Schiffman M, Zhao F, Arbyn M, Prendiville W, Indave Ruiz BI, Mosquera-Metcalfe I, Lauby-Secretan B. PMID: 34758259.
    View in: PubMed   Mentions: 44     Fields:    Translation:HumansPHPublic Health
  10. Prevalence and Incidence of Sexually Transmitted Infection in Injectable Progestin Contraception Users in South Africa. Front Reprod Health. 2021 Jul; 3. Noguchi LM, Marrazzo JM, Richardson B, Hillier SL, Balkus JE, Palanee-Phillips T, Nair G, Panchia R, Piper J, Gomez K, Ramjee G, Chirenje ZM. PMID: 35669097; PMCID: PMC9165437.
    View in: PubMed   Mentions:
  11. Self-collected and clinician-collected anal swabs show modest agreement for HPV genotyping. PLoS One. 2021; 16(4):e0250426. Dube Mandishora RS, Rounge TB, Fitzpatrick M, Christiansen IK, Ambur OH, Lagström S, Stray-Pedersen B, Tommasino M, Palefsky J, Chirenje ZM. PMID: 33901223; PMCID: PMC8075200.
    View in: PubMed   Mentions: 3     Fields:    Translation:HumansCellsPHPublic Health
  12. Effect of injectable progestin-only contraceptives, depot medroxyprogesterone acetate and norethisterone enanthate, on cytokine production during T-cell activation. Am J Reprod Immunol. 2021 07; 86(1):e13405. Matubu AT, Hillier SL, Meyn LA, Stoner KA, Mhlanga F, Mbizvo M, Maramba A, Chirenje ZM, Achilles SL. PMID: 33609312.
    View in: PubMed   Mentions: 3     Fields:    Translation:HumansCellsCTClinical Trials
  13. Treatment approaches for women with positive cervical screening results in low-and middle-income countries. Prev Med. 2021 03; 144:106439. Wentzensen N, Chirenje ZM, Prendiville W. PMID: 33678236.
    View in: PubMed   Mentions: 5     Fields:    Translation:HumansPHPublic Health
  14. Safety, uptake, and use of a dapivirine vaginal ring for HIV-1 prevention in African women (HOPE): an open-label, extension study. Lancet HIV. 2021 02; 8(2):e87-e95. Baeten JM, Palanee-Phillips T, Mgodi NM, Mayo AJ, Szydlo DW, Ramjee G, Gati Mirembe B, Mhlanga F, Hunidzarira P, Mansoor LE, Siva S, Govender V, Makanani B, Naidoo L, Singh N, Nair G, Chinula L, Parikh UM, Mellors JW, Balán IC, Ngure K, van der Straten A, Scheckter R, Garcia M, Peda M, Patterson K, Livant E, Bunge K, Singh D, Jacobson C, Jiao Y, Hendrix CW, Chirenje ZM, Nakabiito C, Taha TE, Jones J, Torjesen K, Nel A, Rosenberg Z, Soto-Torres LE, Hillier SL, Brown ER, MTN-025/HOPE Study Team. PMID: 33539762; PMCID: PMC8038210.
    View in: PubMed   Mentions: 34     Fields:    Translation:HumansCellsCTClinical Trials
  15. Preferences and Acceptability of Vaginal Delivery Forms for HIV Prevention Among Women, Male Partners and Key Informants in South Africa and Zimbabwe: Qualitative Findings. AIDS Behav. 2021 Jan; 25(1):124-138. Musara P, Milford C, Shapley-Quinn MK, Weinrib R, Mutero P, Odoom E, Mgodi NM, Chirenje ZM, Hanif H, Clark MR, Smit J, van der Straten A, Montgomery ET, Quatro Study Team. PMID: 32588257.
    View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic Health
  16. Estimated costs for the delivery of safer conception strategies for HIV-discordant couples in Zimbabwe: a cost analysis. BMC Health Serv Res. 2020 Oct 12; 20(1):940. Hughes CS, Brown J, Murombedzi C, Chirenda T, Chareka G, Mhlanga F, Mateveke B, Gitome S, Makurumure T, Matubu A, Mgodi N, Chirenje Z, Kahn JG. PMID: 33046066; PMCID: PMC7552466.
    View in: PubMed   Mentions: 3     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
  17. Knowledge, attitudes, and practices of cervical Cancer screening among HIV-positive and HIV-negative women participating in human papillomavirus screening in rural Zimbabwe. BMC Womens Health. 2020 07 25; 20(1):153. Fitzpatrick M, Pathipati MP, McCarty K, Rosenthal A, Katzenstein D, Chirenje ZM, Pinsky B. PMID: 32711530; PMCID: PMC7382027.
    View in: PubMed   Mentions: 4     Fields:    Translation:HumansCellsPHPublic Health
  18. Zim CHIC: A cohort study of immune changes in the female genital tract associated with initiation and use of contraceptives. Am J Reprod Immunol. 2020 09; 84(3):e13287. Achilles SL, Meyn LA, Mhlanga FG, Matubu AT, Stoner KA, Beamer MA, Chirenje ZM, Hillier SL. PMID: 32533883; PMCID: PMC7507197.
    View in: PubMed   Mentions: 7     Fields:    Translation:HumansCells
  19. Efficacy is Not Everything: Eliciting Women's Preferences for a Vaginal HIV Prevention Product Using a Discrete-Choice Experiment. AIDS Behav. 2020 May; 24(5):1443-1451. Browne EN, Montgomery ET, Mansfield C, Boeri M, Mange B, Beksinska M, Schwartz JL, Clark MR, Doncel GF, Smit J, Chirenje ZM, van der Straten A. PMID: 31696371; PMCID: PMC6990865.
    View in: PubMed   Mentions: 13     Fields:    Translation:Humans
  20. Antenatal depression: an examination of prevalence and its associated factors among pregnant women attending Harare polyclinics. BMC Pregnancy Childbirth. 2020 Apr 06; 20(1):197. Kaiyo-Utete M, Dambi JM, Chingono A, Mazhandu FSM, Madziro-Ruwizhu TB, Henderson C, Magwali T, Langhaug L, Chirenje ZM. PMID: 32252675; PMCID: PMC7137411.
    View in: PubMed   Mentions: 5     Fields:    Translation:Humans
  21. Use of the dapivirine vaginal ring and effect on cervical cytology abnormalities. AIDS. 2020 03 15; 34(4):559-567. Reddy K, Kelly C, Brown ER, Jeenarain N, Naidoo L, Siva S, Bekker LG, Nair G, Makanani B, Chinula L, Mgodi N, Chirenje Z, Kiweewa FM, Marrazzo J, Bunge K, Soto-Torres L, Piper J, Baeten JM, Palanee-Phillips T, MTN-020/ASPIRE and MTN-003/VOICE Study Teams. PMID: 31764068; PMCID: PMC7262458.
    View in: PubMed   Mentions: 3     Fields:    Translation:HumansCellsCTClinical Trials
  22. Mentored postdoctoral training in Zimbabwe: A report on a successful collaborative effort. J Public Health Afr. 2019 Dec 31; 10(2):1081. Zhou DT, Maponga CC, Madhombiro M, Dube A, Mano R, Nyamhunga A, Machingura I, Manasa J, Hakim J, Chirenje ZM, Mudzviti T, Nhachi C, Ma Q, DiFrancesco R, Masanganise R, Morse GD. PMID: 32257079; PMCID: PMC7118437.
    View in: PubMed   Mentions: 3  
  23. Depot medroxyprogesterone acetate and norethisterone enanthate differentially impact T-cell responses and expression of immunosuppressive markers. Am J Reprod Immunol. 2020 03; 83(3):e13210. Matubu A, Hillier SL, Meyn LA, Stoner KA, Mhlanga F, Mbizvo M, Maramba A, Chirenje ZM, Achilles SL. PMID: 31729087; PMCID: PMC7900783.
    View in: PubMed   Mentions: 1     Fields:    Translation:HumansCells
  24. Human papillomavirus genotype distribution in genital warts among women in Harare-Zimbabwe. J Obstet Gynaecol. 2020 Aug; 40(6):830-836. Manyere NR, Dube Mandishora RS, Magwali T, Mtisi F, Mataruka K, Mtede B, Palefsky JM, Chirenje ZM. PMID: 31790323.
    View in: PubMed   Mentions: 4     Fields:    Translation:HumansCells
  25. Social harms in female-initiated HIV prevention method research: state of the evidence. AIDS. 2019 11 15; 33(14):2237-2244. Montgomery ET, Roberts ST, Nel A, Malherbe M, Torjesen K, Bunge K, Singh D, Baeten JM, Marrazzo J, Chirenje ZM, Kabwigu S, Beigi R, Riddler SA, Gaffour Z, Reddy K, Mansoor LE, Nair G, Woeber K, Moodley J, Jeenarain N, Siva S, Naidoo L, Govender V, Palanee-Phillips T. PMID: 31408030; PMCID: PMC6832829.
    View in: PubMed   Mentions: 8     Fields:    Translation:Humans
  26. Understanding data and information needs for palliative cancer care to inform digital health intervention development in Nigeria, Uganda and Zimbabwe: protocol for a multicountry qualitative study. BMJ Open. 2019 10 31; 9(10):e032166. Okunade K, Bashan Nkhoma K, Salako O, Akeju D, Ebenso B, Namisango E, Soyannwo O, Namukwaya E, Dandadzi A, Nabirye E, Mupaza L, Luyirika E, Ddungu H, Chirenje ZM, Bennett MI, Harding R, Allsop MJ. PMID: 31676657; PMCID: PMC6830840.
    View in: PubMed   Mentions: 8     Fields:    Translation:Humans
  27. Giant mucinous cystadenoma: a case report. J Med Case Rep. 2019 Jun 14; 13(1):181. Gwanzura C, Muyotcha AF, Magwali T, Chirenje ZM, Madziyire MG. PMID: 31196215; PMCID: PMC6567598.
    View in: PubMed   Mentions: 7     Fields:    Translation:Humans
  28. Community-based self-collected human papillomavirus screening in rural Zimbabwe. BMC Public Health. 2019 May 29; 19(Suppl 1):603. Fitzpatrick MB, El-Khatib Z, Katzenstein D, Pinsky BA, Chirenje ZM, McCarty K. PMID: 31138174; PMCID: PMC6538544.
    View in: PubMed   Mentions: 7     Fields:    Translation:HumansPHPublic Health
  29. Tenofovir Gel for Prevention of Herpes Simplex Virus Type 2 Acquisition: Findings From the VOICE Trial. J Infect Dis. 2019 05 24; 219(12):1940-1947. Marrazzo JM, Rabe L, Kelly C, Richardson B, Deal C, Schwartz JL, Chirenje ZM, Piper J, Morrow RA, Hendrix CW, Marzinke MA, Hillier SL, VOICE Study Team. PMID: 30753642; PMCID: PMC6534189.
    View in: PubMed   Mentions: 5     Fields:    Translation:HumansCellsPHPublic Health
  30. End-user preference for and choice of four vaginally delivered HIV prevention methods among young women in South Africa and Zimbabwe: the Quatro Clinical Crossover Study. J Int AIDS Soc. 2019 05; 22(5):e25283. Montgomery ET, Beksinska M, Mgodi N, Schwartz J, Weinrib R, Browne EN, Mphili N, Musara P, Jaggernath M, Ju S, Smit J, Chirenje ZM, Doncel GF, van der Straten A. PMID: 31069957; PMCID: PMC6506690.
    View in: PubMed   Mentions: 30     Fields:    Translation:Humans
  31. hrHPV prevalence and type distribution in rural Zimbabwe: A community-based self-collection study using near-point-of-care GeneXpert HPV testing. Int J Infect Dis. 2019 May; 82:21-29. Fitzpatrick MB, Dube Mandishora RS, Katzenstein DA, McCarty K, Weber J, Sahoo MK, Manasa J, Chirenje ZM, Pinsky BA. PMID: 30807869; PMCID: PMC6538272.
    View in: PubMed   Mentions: 10     Fields:    Translation:HumansCellsPHPublic Health
  32. A case of twin reversed arterial perfusion (TRAP) sequence managed conservatively. Pan Afr Med J. 2019; 32:54. Ziki EM, Chirenje ZM, Madziyire MG. PMID: 31143359; PMCID: PMC6522165.
    View in: PubMed   Mentions:    Fields:    Translation:Humans
  33. Validation of the GenoType® MTBDRplus Ver 2.0 assay for detection of rifampicin and isoniazid resistance in Mycobacterium tuberculosis complex isolates at UZCHS-CTRC TB research laboratory. Int J Mycobacteriol. 2019 Jan-Mar; 8(1):83-88. Stephen S, Muzhizhizhi D, Dhibi N, Chidemo T, Samaneka W, Matubu TA, Hakim JG, Chirenje ZM. PMID: 30860184.
    View in: PubMed   Mentions: 3     Fields:    Translation:HumansCells
  34. Anal human papillomavirus infection in HIV-positive men and women at two opportunistic infections clinics in Harare, Zimbabwe. BMC Public Health. 2018 Nov 14; 18(1):1260. Chinyowa S, Palefsky JM, Chirenje ZM, Makunike-Mutasa R, Munjoma M, Muguti GI. PMID: 30428859; PMCID: PMC6237038.
    View in: PubMed   Mentions: 6     Fields:    Translation:HumansCells
  35. The association of puerperal sepsis with HIV infection at two tertiary hospitals in Zimbabwe. Int J Gynaecol Obstet. 2019 Jan; 144(1):67-72. Majangara R, Chirenje ZM, Gidiri MF. PMID: 30343490; PMCID: PMC6283678.
    View in: PubMed   Mentions:    Fields:    Translation:Humans
  36. HIV infection in patients with sexually transmitted infections in Zimbabwe - Results from the Zimbabwe STI etiology study. PLoS One. 2018; 13(6):e0198683. Kilmarx PH, Gonese E, Lewis DA, Chirenje ZM, Barr BAT, Latif AS, Gwanzura L, Handsfield HH, Machiha A, Mugurungi O, Rietmeijer CA. PMID: 29889865; PMCID: PMC5995434.
    View in: PubMed   Mentions: 8     Fields:    Translation:Humans
  37. The Etiology of Vaginal Discharge Syndrome in Zimbabwe: Results from the Zimbabwe STI Etiology Study. Sex Transm Dis. 2018 06; 45(6):422-428. Chirenje ZM, Dhibi N, Handsfield HH, Gonese E, Tippett Barr B, Gwanzura L, Latif AS, Maseko DV, Kularatne RS, Tshimanga M, Kilmarx PH, Machiha A, Mugurungi O, Rietmeijer CA. PMID: 29465674; PMCID: PMC6879447.
    View in: PubMed   Mentions: 9     Fields:    Translation:HumansAnimalsCells
  38. Impact of contraceptive initiation on vaginal microbiota. Am J Obstet Gynecol. 2018 06; 218(6):622.e1-622.e10. Achilles SL, Austin MN, Meyn LA, Mhlanga F, Chirenje ZM, Hillier SL. PMID: 29505773; PMCID: PMC5990849.
    View in: PubMed   Mentions: 48     Fields:    Translation:HumansCells
  39. How Presentation of Drug Detection Results Changed Reports of Product Adherence in South Africa, Uganda and Zimbabwe. AIDS Behav. 2018 03; 22(3):877-886. Musara P, Montgomery ET, Mgodi NM, Woeber K, Akello CA, Hartmann M, Cheng H, Levy L, Katz A, Grossman CI, Chirenje ZM, van der Straten A, Mensch B, Microbicide Trials Network-003D Study Team. PMID: 28110473; PMCID: PMC5587392.
    View in: PubMed   Mentions: 5     Fields:    Translation:HumansPHPublic Health
  40. Microbiology and clinical outcomes of puerperal sepsis: a prospective cohort study. J Obstet Gynaecol. 2018 Jul; 38(5):635-641. Majangara R, Gidiri MF, Chirenje ZM. PMID: 29447024.
    View in: PubMed   Mentions: 12     Fields:    Translation:Humans
  41. Misreporting of contraceptive hormone use in clinical research participants. Contraception. 2018 04; 97(4):346-353. Achilles SL, Mhlanga FG, Musara P, Poloyac SM, Chirenje ZM, Hillier SL. PMID: 28966052; PMCID: PMC5858917.
    View in: PubMed   Mentions: 21     Fields:    Translation:Humans
  42. The fourth generation AlereTM HIV Combo rapid test improves detection of acute infection in MTN-003 (VOICE) samples. J Clin Virol. 2017 09; 94:15-21. Livant E, Heaps A, Kelly C, Maharaj R, Samsunder N, Nhlangulela L, Karugaba P, Panchia R, Marrazzo J, Chirenje ZM, Parikh UM, VOICE Study Team. PMID: 28710996; PMCID: PMC5790424.
    View in: PubMed   Mentions: 16     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
  43. Genotypic diversity of anogenital human papillomavirus in women attending cervical cancer screening in Harare, Zimbabwe. J Med Virol. 2017 09; 89(9):1671-1677. Dube Mandishora RS, Christiansen IK, Chin'ombe N, Duri K, Ngara B, Rounge TB, Meisal R, Ambur OH, Palefsky JM, Stray-Pedersen B, Chirenje ZM. PMID: 28390142.
    View in: PubMed   Mentions: 10     Fields:    Translation:HumansCells
  44. Differences in Cumulative Exposure and Adherence to Tenofovir in the VOICE, iPrEx OLE, and PrEP Demo Studies as Determined via Hair Concentrations. AIDS Res Hum Retroviruses. 2017 08; 33(8):778-783. Koss CA, Bacchetti P, Hillier SL, Livant E, Horng H, Mgodi N, Mirembe BG, Gomez Feliciano K, Horn S, Liu AY, Glidden DV, Grant RM, Benet LZ, Louie A, van der Straten A, Chirenje ZM, Marrazzo JM, Gandhi M. PMID: 28253024; PMCID: PMC5564054.
    View in: PubMed   Mentions: 44     Fields:    
  45. Risk Factors for Incidence of Sexually Transmitted Infections Among Women in a Human Immunodeficiency Virus Chemoprevention Trial: VOICE (MTN-003). Sex Transm Dis. 2017 03; 44(3):135-140. Chirenje ZM, Gundacker HM, Richardson B, Rabe L, Gaffoor Z, Nair GL, Mirembe BG, Piper JM, Hillier S, Marrazzo J. PMID: 28178109; PMCID: PMC5535309.
    View in: PubMed   Mentions: 8     Fields:    Translation:Humans
  46. Contraceptive Use and Pregnancy Incidence Among Women Participating in an HIV Prevention Trial. J Womens Health (Larchmt). 2017 06; 26(6):670-676. Akello CA, Bunge KE, Nakabiito C, Mirembe BG, Fowler MG, Mishra A, Marrazzo J, Chirenje ZM, Celum C, Balkus JE. PMID: 28437215; PMCID: PMC5512296.
    View in: PubMed   Mentions: 3     Fields:    Translation:Humans
  47. Adult Hematology and Clinical Chemistry Laboratory Reference Ranges in a Zimbabwean Population. PLoS One. 2016; 11(11):e0165821. Samaneka WP, Mandozana G, Tinago W, Nhando N, Mgodi NM, Bwakura-Dangarembizi MF, Munjoma MW, Gomo ZA, Chirenje ZM, Hakim JG. PMID: 27812172; PMCID: PMC5094654.
    View in: PubMed   Mentions: 11     Fields:    Translation:Humans
  48. Reporting of Adherence in the VOICE Trial: Did Disclosure of Product Nonuse Increase at the Termination Visit? AIDS Behav. 2016 11; 20(11):2654-2661. Mensch BS, Brown ER, Liu K, Marrazzo J, Chirenje ZM, Gomez K, Piper J, Patterson K, van der Straten A. PMID: 26906023; PMCID: PMC5354168.
    View in: PubMed   Mentions: 12     Fields:    Translation:HumansPHPublic Health
  49. Healthcare providers' perspectives on the acceptability and uptake of HPV vaccines in Zimbabwe. J Psychosom Obstet Gynaecol. 2016 12; 37(4):147-155. Crann SE, Barata PC, Mitchell R, Mawhinney L, Thistle P, Chirenje ZM, Stewart DE. PMID: 27400371.
    View in: PubMed   Mentions: 4     Fields:    Translation:Humans
  50. An Empiric HIV Risk Scoring Tool to Predict HIV-1 Acquisition in African Women. J Acquir Immune Defic Syndr. 2016 07 01; 72(3):333-43. Balkus JE, Brown E, Palanee T, Nair G, Gafoor Z, Zhang J, Richardson BA, Chirenje ZM, Marrazzo JM, Baeten JM. PMID: 26918545; PMCID: PMC4911322.
    View in: PubMed   Mentions: 75     Fields:    Translation:HumansCells
  51. Corrigendum to "oral and injectable contraceptive use and HIV acquisition risk among women in four African countries: a secondary analysis of data from a microbicide trial" [Contraception 2016; 93 (1): 25-31]. Contraception. 2016 Jul; 94(1):95. Balkus JE, Brown ER, Hillier SL, Coletti A, Ramjee G, Mgodi N, Makanani B, Reid C, Martinson F, Soto-Torres L, Abdool Karim SS, Chirenje ZM. PMID: 27085419.
    View in: PubMed   Mentions: 1     Fields:    
  52. Bone Mineral Density Changes Among Young, Healthy African Women Receiving Oral Tenofovir for HIV Preexposure Prophylaxis. J Acquir Immune Defic Syndr. 2016 Mar 01; 71(3):287-94. Mirembe BG, Kelly CW, Mgodi N, Greenspan S, Dai JY, Mayo A, Piper J, Akello CA, Kiweewa FM, Magure T, Nakabiito C, Marrazzo JM, Chirenje ZM, Riddler SA, MTN-003B Protocol Team. PMID: 26866954; PMCID: PMC4755358.
    View in: PubMed   Mentions: 28     Fields:    Translation:HumansPHPublic Health
  53. Use of a Vaginal Ring Containing Dapivirine for HIV-1 Prevention in Women. N Engl J Med. 2016 12 01; 375(22):2121-2132. Baeten JM, Palanee-Phillips T, Brown ER, Schwartz K, Soto-Torres LE, Govender V, Mgodi NM, Matovu Kiweewa F, Nair G, Mhlanga F, Siva S, Bekker LG, Jeenarain N, Gaffoor Z, Martinson F, Makanani B, Pather A, Naidoo L, Husnik M, Richardson BA, Parikh UM, Mellors JW, Marzinke MA, Hendrix CW, van der Straten A, Ramjee G, Chirenje ZM, Nakabiito C, Taha TE, Jones J, Mayo A, Scheckter R, Berthiaume J, Livant E, Jacobson C, Ndase P, White R, Patterson K, Germuga D, Galaska B, Bunge K, Singh D, Szydlo DW, Montgomery ET, Mensch BS, Torjesen K, Grossman CI, Chakhtoura N, Nel A, Rosenberg Z, McGowan I, Hillier S, MTN-020–ASPIRE Study Team. PMID: 26900902; PMCID: PMC4993693.
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  54. Oral and injectable contraceptive use and HIV acquisition risk among women in four African countries: a secondary analysis of data from a microbicide trial. Contraception. 2016 Jan; 93(1):25-31. Balkus JE, Brown ER, Hillier SL, Coletti A, Ramjee G, Mgodi N, Makanani B, Reid C, Martinson F, Soto-Torres L, Abdool Karim SS, Chirenje ZM. PMID: 26519646; PMCID: PMC4688130.
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  55. Age-Disparate Partnerships and Risk of HIV-1 Acquisition Among South African Women Participating in the VOICE Trial. J Acquir Immune Defic Syndr. 2015 Oct 01; 70(2):212-7. Balkus JE, Nair G, Montgomery ET, Mishra A, Palanee-Phillips T, Ramjee G, Panchia R, Selepe P, Richardson BA, Chirenje ZM, Marrazzo JM. PMID: 26049280; PMCID: PMC4573287.
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  56. Risk of HIV-1 acquisition among women who use diff erent types of injectable progestin contraception in South Africa: a prospective cohort study. Lancet HIV. 2015 Jul; 2(7):e279-87. Noguchi LM, Richardson BA, Baeten JM, Hillier SL, Balkus JE, Chirenje ZM, Bunge K, Ramjee G, Nair G, Palanee-Phillips T, Selepe P, van der Straten A, Parikh UM, Gomez K, Piper JM, Watts DH, Marrazzo JM, VOICE Study Team. PMID: 26155597; PMCID: PMC4491329.
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  57. Pharmacological Measures of Treatment Adherence and Risk of HIV Infection in the VOICE Study. J Infect Dis. 2016 Feb 01; 213(3):335-42. Dai JY, Hendrix CW, Richardson BA, Kelly C, Marzinke M, Chirenje ZM, Marrazzo JM, Brown ER. PMID: 26123563; PMCID: PMC4704663.
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  58. Factors associated with bone mineral density in healthy African women. Arch Osteoporos. 2015; 10:206. Mgodi NM, Kelly C, Gati B, Greenspan S, Dai JY, Bragg V, Livant E, Piper JM, Nakabiito C, Magure T, Marrazzo JM, Chirenje ZM, Riddler SA, MTN-003B Protocol Team. PMID: 25680424; PMCID: PMC4564062.
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  59. Tenofovir-based preexposure prophylaxis for HIV infection among African women. N Engl J Med. 2015 Feb 05; 372(6):509-18. Marrazzo JM, Ramjee G, Richardson BA, Gomez K, Mgodi N, Nair G, Palanee T, Nakabiito C, van der Straten A, Noguchi L, Hendrix CW, Dai JY, Ganesh S, Mkhize B, Taljaard M, Parikh UM, Piper J, Mâsse B, Grossman C, Rooney J, Schwartz JL, Watts H, Marzinke MA, Hillier SL, McGowan IM, Chirenje ZM, VOICE Study Team. PMID: 25651245; PMCID: PMC4341965.
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  60. Hematological and biochemical laboratory reference intervals for Zimbabwean adolescents. Clin Lab. 2015; 61(1-2):101-11. Gomani P, Matubu AT, Mujuru HA, Munjoma MW, Tinago W, Mandozana G, Hakim JG, Gomo ZA, Chirenje ZM. PMID: 25807644.
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  61. Trends in the incidence of cancer in the black population of Harare, Zimbabwe 1991-2010. Int J Cancer. 2013 Aug 01; 133(3):721-9. Chokunonga E, Borok MZ, Chirenje ZM, Nyakabau AM, Parkin DM. PMID: 23364833.
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  62. Mucosal Escherichia coli bactericidal activity and immune mediators are associated with HIV-1 seroconversion in women participating in the HPTN 035 trial. J Infect Dis. 2012 Dec 15; 206(12):1931-5. Dezzutti CS, Richardson BA, Marrazzo JM, Tugetman J, Ramjee G, Taha T, Chirenje ZM, Abdool Karim SS, Hillier SL, Herold BC, MTN Biomedical Sciences Working Group, HPTN 035 Protocol Team. PMID: 22966121; PMCID: PMC3502373.
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  63. Utility of colposcopy in a phase 2 portion of a microbicide clinical trial of BufferGel and 0.5% PRO 2000 Gel. J Int AIDS Soc. 2012 Aug 27; 15(2):17376. Chirenje ZM, Mâsse BR, Maslankowski LA, Ramjee G, Coletti AS, Tembo TN, Magure TM, Soto-Torres L, Kelly C, Hillier S, Karim A. PMID: 22944480; PMCID: PMC3494172.
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  64. Safety and effectiveness of BufferGel and 0.5% PRO2000 gel for the prevention of HIV infection in women. AIDS. 2011 Apr 24; 25(7):957-66. Abdool Karim SS, Richardson BA, Ramjee G, Hoffman IF, Chirenje ZM, Taha T, Kapina M, Maslankowski L, Coletti A, Profy A, Moench TR, Piwowar-Manning E, Mâsse B, Hillier SL, Soto-Torres L, HIV Prevention Trials Network (HPTN) 035 Study Team. PMID: 21330907; PMCID: PMC3083640.
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  65. Cancer survival in Harare, Zimbabwe, 1993-1997. IARC Sci Publ. 2011; (162):249-55. Chokunonga E, Borok MZ, Chirenje ZM, Nyabakau AM, Parkin DM. PMID: 21675430.
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  66. Antiretroviral-based HIV prevention strategies for women. Expert Rev Anti Infect Ther. 2010 Oct; 8(10):1177-86. Chirenje ZM, Marrazzo J, Parikh UM. PMID: 20954882; PMCID: PMC4381115.
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  67. Compliance and loss to follow up of HIV negative and positive mothers recruited from a PMTCT programme in Zimbabwe. Cent Afr J Med. 2007 May-Aug; 53(5-8):25-30. Kurewa NE, Munjoma MM, Chirenje ZM, Rusakaniko S, Hussain A, Stray-Pedersen B. PMID: 20355678.
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  68. Acceptability of heat treating breast milk to prevent mother-to-child transmission of human immunodeficiency virus in Zimbabwe: a qualitative study. J Hum Lact. 2006 Feb; 22(1):48-60. Israel-Ballard KA, Maternowska MC, Abrams BF, Morrison P, Chitibura L, Chipato T, Chirenje ZM, Padian NS, Chantry CJ. PMID: 16467287.
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  69. HIV and cancer of the cervix. Best Pract Res Clin Obstet Gynaecol. 2005 Apr; 19(2):269-76. Chirenje ZM. PMID: 15778115.
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  70. The CONRAD/WHO Update 2000 colposcopy manual: how well is it working? J Acquir Immune Defic Syndr. 2004 Oct; 37 Suppl 3:S150-1. Njoroge B, Chirenje ZM, Pandey B, Mirembe F, Joshi S, Low-Beer N, Maslankowski LA. PMID: 16419263.
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  71. Bacterial vaginosis and intravaginal practices: association with HIV. Cent Afr J Med. 2004 May-Jun; 50(5-6):41-6. Mbizvo ME, Musya SE, Stray-Pedersen B, Chirenje Z, Hussain A. PMID: 15881309.
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  72. Situation analysis for cervical cancer diagnosis and treatment in east, central and southern African countries. Bull World Health Organ. 2001; 79(2):127-32. Chirenje ZM, Rusakaniko S, Kirumbi L, Ngwalle EW, Makuta-Tlebere P, Kaggwa S, Mpanju-Shumbusho W, Makoae L. PMID: 11242819; PMCID: PMC2566349.
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  73. Cancer of the cervix: knowledge, beliefs and screening behaviours of health workers in Mudzi District in Mashonaland East Province, Zimbabwe. Cent Afr J Med. 2003 Jul-Aug; 49(7-8):83-6. Tarwireyi F, Chirenje ZM, Rusakaniko S. PMID: 15214279.
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  74. Effect of HIV Disease in Treatment Outcome of Cervical Squamous Intraepithelial Lesions Among Zimbabwean Women. J Low Genit Tract Dis. 2003 Jan; 7(1):16-21. Chirenje ZM, Rusakaniko S, Akino V, Munjoma M, Mlingo M. PMID: 17051039.
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  75. A randomised clinical trial of loop electrosurgical excision procedure (LEEP) versus cryotherapy in the treatment of cervical intraepithelial neoplasia. J Obstet Gynaecol. 2001 Nov; 21(6):617-21. Chirenje ZM, Rusakaniko S, Akino V, Mlingo M. PMID: 12521783.
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  76. Topical vaginal microbicides in HIV/STI prevention. Cent Afr J Med. 2001 Aug; 47(8):209-10. Chirenje ZM. PMID: 12808769.
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  77. Phase 1 trial of the topical microbicide BufferGel: safety results from four international sites. J Acquir Immune Defic Syndr. 2001 Jan 01; 26(1):21-7. van De Wijgert J, Fullem A, Kelly C, Mehendale S, Rugpao S, Kumwenda N, Chirenje Z, Joshi S, Taha T, Padian N, Bollinger R, Nelson K. PMID: 11176265.
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  78. Adjunctive testing for cervical cancer in low resource settings with visual inspection, HPV, and the Pap smear. Int J Gynaecol Obstet. 2001 Jan; 72(1):47-53. Blumenthal PD, Gaffikin L, Chirenje ZM, McGrath J, Womack S, Shah K. PMID: 11146077.
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  79. The management of cervical intra-epithelial neoplasia. Cent Afr J Med. 2000 Nov; 46(11):309-10. Chirenje Z. PMID: 12002122.
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  80. Effect of intravaginal practices on the vaginal and cervical mucosa of Zimbabwean women. J Acquir Immune Defic Syndr. 2000 May 01; 24(1):62-7. van de Wijgert JH, Chirenje ZM, Iliff V, Mbizvo MT, Mason PR, Gwanzura L, Shiboski S, Padian NS. PMID: 10877497.
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  81. Intravaginal practices, vaginal flora disturbances, and acquisition of sexually transmitted diseases in Zimbabwean women. J Infect Dis. 2000 Feb; 181(2):587-94. van De Wijgert JH, Mason PR, Gwanzura L, Mbizvo MT, Chirenje ZM, Iliff V, Shiboski S, Padian NS. PMID: 10669342.
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  82. HPV-based cervical cancer screening in a population at high risk for HIV infection. Int J Cancer. 2000 Jan 15; 85(2):206-10. Womack SD, Chirenje ZM, Gaffikin L, Blumenthal PD, McGrath JA, Chipato T, Ngwalle S, Munjoma M, Shah KV. PMID: 10629079.
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  83. Evaluation of a human papillomavirus assay in cervical screening in Zimbabwe. BJOG. 2000 Jan; 107(1):33-8. Womack SD, Chirenje ZM, Blumenthal PD, Gaffikin L, McGrath JA, Chipato T, Ngwalle E, Shah KV. PMID: 10645859.
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  84. Visual inspection of the cervix as a primary means of cervical cancer screening: results of a pilot study. Cent Afr J Med. 1999 Feb; 45(2):30-3. Chirenje ZM, Chipato T, Kasule J, Rusakaniko S. PMID: 10444896.
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  85. Situation analysis for cervical cancer diagnosis and treatment in Zimbabwe. Cent Afr J Med. 1998 Dec; 44(12):307-10. Chirenje ZM, Rusakaniko S, Chipato T, Mpanju-Shumbusho W, Ngwalle E, Kirumbi LW, Makuta-Tlebere P, Kaggwa S. PMID: 10921202.
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  86. Cervical cancer screening in a rural population of Zimbabwe. Cent Afr J Med. 1997 Sep; 43(9):246-51. Thistle PJ, Chirenje ZM. PMID: 9509642.
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  87. Management of the patient with an abnormal Papanicolaou smear. Cent Afr J Med. 1994 May; 40(5):131-4. Chirenje ZM. PMID: 7954725.
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  88. Screening for cervical cancer: experience from the Colposcopy Clinic at Harare Hospital. Cent Afr J Med. 1993 Nov; 39(11):222-4. Chirenje ZM, Akino V. PMID: 8055551.
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