Deborah Cohan, MD, MPH
Professor, Departments of Obstetrics, Gynecology & Reproductive Sciences and Family & Community Medicine
Medical Director, HIVE/Bay Area Perinatal AIDS Center (BAPAC)
Clinical Director, National Perinatal HIV Hotline and Clinicians Network
Dr. Cohan provides preconception, prenatal and gynecologic care for HIV-infected women and HIV-affected couples. Dr. Cohan is also a member of the Department of Health and Human Services Panel on Antiretroviral Guidelines for Adults and Adolescents. Her research interests include prenatal HIV testing strategies, the use of combined antiretroviral therapy during pregnancy and lactation in resource-limited settings, and prevention of placental malaria among HIV-infected pregnant women.
Areas of interest:
- Women and HIV
- Perinatal HIV prevention
- Prevention of placental malaria
In the news:
- Large Bay Area blood bank still turning away gay, bisexual men who meet US rules | San Francisco Chronicle
Publications:
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Anemia and Micronutrient Status during Pregnancy, and Their Associations with Obstetric and Infant Outcomes among HIV-Infected Ugandan Women Receiving Antiretroviral Therapy. Curr Dev Nutr. 2020 May; 4(5):nzaa075. Finkelstein JL, Herman HS, Plenty A, Mehta S, Natureeba P, Clark TD, Kamya MR, Ruel T, Charlebois ED, Cohan D, Havlir D, Young SL. PMID: 32440638.View in: PubMed Mentions:
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Response to Letter. Obstet Gynecol. 2020 02; 135(2):484-485. Hahn MU, Sheran N, Weber S, Cohan D, Obedin-Maliver J. PMID: 31977791.
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Providing Patient-Centered Perinatal Care for Transgender Men and Gender-Diverse Individuals: A Collaborative Multidisciplinary Team Approach. Obstet Gynecol. 2019 11; 134(5):959-963. Hahn M, Sheran N, Weber S, Cohan D, Obedin-Maliver J. PMID: 31599839.
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Miscarriage among women in the United States Women's Interagency HIV Study, 1994-2017. Am J Obstet Gynecol. 2019 10; 221(4):347.e1-347.e13. Wall KM, Haddad LB, Mehta CC, Golub ET, Rahangdale L, Dionne-Odom J, Karim R, Wright RL, Minkoff H, Cohen M, Kassaye SG, Cohan D, Ofotokun I, Cohn SE. PMID: 31136732.
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Empowering HIV-infected women in low-resource settings: A pilot study evaluating a patient-centered HIV prevention strategy for reproduction in Kisumu, Kenya. PLoS One. 2019; 14(3):e0212656. Mmeje O, Njoroge B, Wekesa P, Murage A, Ondondo RO, van der Poel S, Guzé MA, Shade SB, Bukusi EA, Cohan D, Cohen CR. PMID: 30840672.
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Racist Like Me - A Call to Self-Reflection and Action for White Physicians. N Engl J Med. 2019 Feb 28; 380(9):805-807. Cohan D. PMID: 30811907.
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ACOG Committee Opinion No. 752: Prenatal and Perinatal Human Immunodeficiency Virus Testing. Obstet Gynecol. 2019 01; 133(1):187. Pollock L, Cohan D, Pecci CC, Mittal P. PMID: 30575656.
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Estradiol Levels Are Altered in Human Immunodeficiency Virus-Infected Pregnant Women Randomized to Efavirenz-Versus Lopinavir/Ritonavir-Based Antiretroviral Therapy. Clin Infect Dis. 2018 01 18; 66(3):428-436. McDonald CR, Conroy AL, Gamble JL, Papp E, Hawkes M, Olwoch P, Natureeba P, Kamya M, Silverman M, Cohan D, Koss CA, Dorsey G, Kain KC, Serghides L. PMID: 29136115.
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Protective Effect of Indoor Residual Spraying of Insecticide on Preterm Birth Among Pregnant Women With HIV Infection in Uganda: A Secondary Data Analysis. J Infect Dis. 2017 12 19; 216(12):1541-1549. Roh ME, Shiboski S, Natureeba P, Kakuru A, Muhindo M, Ochieng T, Plenty A, Koss CA, Clark TD, Awori P, Nakalambe M, Cohan D, Jagannathan P, Gosling R, Havlir DV, Kamya MR, Dorsey G. PMID: 29029337.
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Altered angiogenesis as a common mechanism underlying preterm birth, small for gestational age, and stillbirth in women living with HIV. Am J Obstet Gynecol. 2017 12; 217(6):684.e1-684.e17. Conroy AL, McDonald CR, Gamble JL, Olwoch P, Natureeba P, Cohan D, Kamya MR, Havlir DV, Dorsey G, Kain KC. PMID: 29031892.
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Intermittent Preventive Treatment With Dihydroartemisinin-Piperaquine for the Prevention of Malaria Among HIV-Infected Pregnant Women. J Infect Dis. 2017 07 01; 216(1):29-35. PMID: 28329368.
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Safer Conception and Contraceptive Counseling By Providers of Men Living With HIV in San Francisco. J Assoc Nurses AIDS Care. 2017 Nov - Dec; 28(6):964-970. PMID: 28709752.
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Offering pre-exposure prophylaxis for HIV prevention to pregnant and postpartum women: a clinical approach. J Int AIDS Soc. 2017 03 08; 20(Suppl 1):21295. PMID: 28361503.
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Viral Suppression and Retention in Care up to 5 Years After Initiation of Lifelong ART During Pregnancy (Option B+) in Rural Uganda. . 2017 Mar 01; 74(3):279-284. PMID: 27828878.View in: PubMed Mentions:
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Genital Herpes. N Engl J Med. 2016 11 10; 375(19):1906. PMID: 27959657.
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"Is It All Right for Me to Have a Baby or Not?": Men Living With HIV Discuss Fertility Desires and Interactions With Providers. J Assoc Nurses AIDS Care. 2017 Jan - Feb; 28(1):118-129. PMID: 28010827.
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Malaria burden in a birth cohort of HIV-exposed uninfected Ugandan infants living in a high malaria transmission setting. Malar J. 2016 Oct 18; 15(1):500. PMID: 27756308.
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Trends of and factors associated with live-birth and abortion rates among HIV-positive and HIV-negative women. Am J Obstet Gynecol. 2017 Jan; 216(1):71.e1-71.e16. PMID: 27640942.
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Use of HIV pre-exposure prophylaxis during the preconception, antepartum and postpartum periods at two United States medical centers. Am J Obstet Gynecol. 2016 Nov; 215(5):632.e1-632.e7. PMID: 27448959.
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Antiretroviral Resistance and Pregnancy Characteristics of Women with Perinatal and Nonperinatal HIV Infection. Infect Dis Obstet Gynecol. 2016; 2016:4897501. PMID: 27413359.
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The Exclusion of Sperm Donation on the Basis of Sexual Practices: Time for a Policy Update. Obstet Gynecol. 2016 06; 127(6):1097-1099. PMID: 27159761.
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Brief Report: Food Insufficiency Is Associated With Lack of Sustained Viral Suppression Among HIV-Infected Pregnant and Breastfeeding Ugandan Women. . 2016 Mar 01; 71(3):310-5. PMID: 26397935.View in: PubMed Mentions:
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A clinical approach to elimination of perinatal HIV transmission in resource-rich settings. Int J Gynaecol Obstet. 2015 Dec; 131(3):309-10. PMID: 26381200.
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"I Have Remained Strong Because of That Food": Acceptability and Use of Lipid-Based Nutrient Supplements Among Pregnant HIV-Infected Ugandan Women Receiving Combination Antiretroviral Therapy. AIDS Behav. 2015 Aug; 19(8):1535-47. PMID: 25416075.
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The changing landscape for HIV-serodifferent couples desiring a child. Am J Obstet Gynecol. 2015 Nov; 213(5):746. PMID: 26116098.
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The FACTS about women and pre-exposure prophylaxis. Lancet HIV. 2015 Jun; 2(6):e228. PMID: 26423194.
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Hair concentrations of antiretrovirals predict viral suppression in HIV-infected pregnant and breastfeeding Ugandan women. AIDS. 2015 Apr 24; 29(7):825-30. PMID: 25985404.
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Efficacy and safety of lopinavir/ritonavir versus efavirenz-based antiretroviral therapy in HIV-infected pregnant Ugandan women. AIDS. 2015 Jan 14; 29(2):183-91. PMID: 25426808.
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Household food insecurity, maternal nutritional status, and infant feeding practices among HIV-infected Ugandan women receiving combination antiretroviral therapy. Matern Child Health J. 2014 Nov; 18(9):2044-53. PMID: 24585398.
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Reply to Kennedy et al. Clin Infect Dis. 2015 Feb 15; 60(4):674. PMID: 25352590.
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Risk factors for preterm birth among HIV-infected pregnant Ugandan women randomized to lopinavir/ritonavir- or efavirenz-based antiretroviral therapy. . 2014 Oct 01; 67(2):128-35. PMID: 25072616.View in: PubMed Mentions:
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Lopinavir/ritonavir-based antiretroviral treatment (ART) versus efavirenz-based ART for the prevention of malaria among HIV-infected pregnant women. J Infect Dis. 2014 Dec 15; 210(12):1938-45. PMID: 24958908.
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Breastfeeding and HIV-infected women in the United States: harm reduction counseling strategies. Clin Infect Dis. 2014 Jul 15; 59(2):304-9. PMID: 24771330.
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Anemia, vitamin B12, and folate statuses during pregnancy, and their association with obstetric outcomes among HIV-infected Ugandan women receiving ART (804.8). The FASEB Journal. 2014 Apr 1; 28. Julia Finkelstein, Albert Plenty, Saurabh Mehta, Paul Natureeba, Tamara Clark, Moses Kamya, Edwin Charlebois, Deborah Cohan, Diane Havlir, Sera Young. .View in: Publisher Site Mentions:
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Early experiences implementing pre-exposure prophylaxis (PrEP) for HIV prevention in San Francisco. PLoS Med. 2014 Mar; 11(3):e1001613. PMID: 24595035.
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Pregnancy intentions among women living with HIV in the United States. . 2014 Mar 01; 65(3):306-11. PMID: 24525467.View in: PubMed Mentions:
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Pharmacokinetics of lopinavir/ritonavir and efavirenz in food insecure HIV-infected pregnant and breastfeeding women in Tororo, Uganda. J Clin Pharmacol. 2014 Feb; 54(2):121-32. PMID: 24038035.
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Hair and plasma data show that lopinavir, ritonavir, and efavirenz all transfer from mother to infant in utero, but only efavirenz transfers via breastfeeding. . 2013 Aug 15; 63(5):578-84. PMID: 24135775.View in: PubMed Mentions:
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Time to viral load suppression in antiretroviral-naive and -experienced HIV-infected pregnant women on highly active antiretroviral therapy: implications for pregnant women presenting late in gestation. BJOG. 2013 Nov; 120(12):1534-47. PMID: 23924192.
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Acceptability and feasibility of serial HIV antibody testing during pregnancy/postpartum and male partner testing in Tororo, Uganda. AIDS Care. 2014; 26(3):360-6. PMID: 23909832.
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Safer conception options for HIV serodifferent couples in the United States: the experience of the National Perinatal HIV Hotline and Clinicians' Network. . 2013 Aug 01; 63(4):e140-1. PMID: 23807158.View in: PubMed Mentions:
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Neonatal mortality in HIV-exposed infants born to women receiving combination antiretroviral therapy in Rural Uganda. J Trop Pediatr. 2013 Dec; 59(6):441-6. PMID: 23764539.
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The cost-effectiveness of repeat HIV testing during pregnancy in a resource-limited setting. . 2013 Jun 01; 63(2):195-200. PMID: 23392461.View in: PubMed Mentions:
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CDC should reverse its recommendation against semen washing-intrauterine insemination for HIV-serodifferent couples. Am J Obstet Gynecol. 2013 Sep; 209(3):284. PMID: 23628260.
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WHO option B+: early experience of antiretroviral therapy sequencing after cessation of breastfeeding and risk of dermatologic toxicity. . 2013 Mar 01; 62(3):e101-3. PMID: 23924639.View in: PubMed Mentions:
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Preexposure prophylaxis for the prevention of HIV transmission to women. AIDS. 2013 Jan 02; 27(1):F1-5. PMID: 22914582.
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737: Acceptability of serial HIV testing and partner testing during pregnancy and lactation in Tororo, Uganda. American Journal of Obstetrics and Gynecology. 2013 Jan 1; 208(1):s310. Lena Kim, Emmanuel Arinaitwe, Bridget Nzarubara, Tamara Clark, Pius Okong, Edwin Charlebois, Diane Havlir, Deborah Cohan. .View in: Publisher Site Mentions:
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HIV and reproduction: fertility, contraception, and preconception issues and interventions. Infect Dis Obstet Gynecol. 2012; 2012:736864. PMID: 23345960.
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Antiretrovirals and safer conception for HIV-serodiscordant couples. Curr Opin HIV AIDS. 2012 Nov; 7(6):569-78. PMID: 23032734.
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Trends in contraceptive use among women with human immunodeficiency virus. Obstet Gynecol. 2012 Oct; 120(4):783-90. PMID: 22996095.
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Evaluating safer conception options for HIV-serodiscordant couples (HIV-infected female/HIV-uninfected male): a closer look at vaginal insemination. Infect Dis Obstet Gynecol. 2012; 2012:587651. PMID: 22927714.
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Maternal nutritional status predicts adverse birth outcomes among HIV-infected rural Ugandan women receiving combination antiretroviral therapy. PLoS One. 2012; 7(8):e41934. PMID: 22879899.
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Breastfeeding practices and beliefs among HIV+ pregnant and lactating women on antiretroviral therapy in rural Uganda indicate obstacles to following national guidelines. The FASEB Journal. 2012 Apr 1; 26:653.3-653.3. Barnabas Kahiira Natamba, Marion Robine, Flavia Luwedde, Julia Mwesigwa, Paul Natureeba, Beth Osterbauer, Veronica Ades, Tamara Clark, Edwin Charlebois, Albert Plenty, Diane Havlir, Deborah Cohan, Jane Achan, Sera Young. .View in: Publisher Site Mentions:
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Contraceptive use and barriers to access among newly arrested women. J Correct Health Care. 2012 Apr; 18(2):111-9. PMID: 22419640.
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Interferon gamma release assay compared with the tuberculin skin test for latent tuberculosis detection in pregnancy. Obstet Gynecol. 2011 Dec; 118(6):1363-1370. PMID: 22105266.
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Group B Streptococcus colonization by HIV status in pregnant women: prevalence and risk factors. J Womens Health (Larchmt). 2011 Nov; 20(11):1737-41. PMID: 22011210.
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Safer conception options for HIV-serodiscordant couples. Am J Obstet Gynecol. 2012 Jan; 206(1):e21; author reply e21-2. PMID: 21974991.
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Perinatal depressive symptoms in HIV-infected versus HIV-uninfected women: a prospective study from preconception to postpartum. J Womens Health (Larchmt). 2011 Sep; 20(9):1287-95. PMID: 21732738.
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Current knowledge and future research on infant feeding in the context of HIV: basic, clinical, behavioral, and programmatic perspectives. Adv Nutr. 2011 May; 2(3):225-43. PMID: 22332055.
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Relative time to pregnancy among HIV-infected and uninfected women in the Women's Interagency HIV Study, 2002-2009. AIDS. 2011 Mar 13; 25(5):707-11. Linas BS, Minkoff H, Cohen MH, Karim R, Cohan D, Wright RL, Young M, Watts DH, Golub ET. PMID: 21297418.
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The human fetal immune response to hepatitis C virus exposure in utero. J Infect Dis. 2011 Jan 15; 203(2):196-206. Babik JM, Cohan D, Monto A, Hartigan-O'Connor DJ, McCune JM. PMID: 21288819.
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636: Should pregnant women have repeat HIV testing at 24 weeks or 35 weeks gestational age to maximally reduce vertical transmission?. American Journal of Obstetrics and Gynecology. 2011 Jan 1; 204(1):s252. Lena H. Kim, Maria I. Rodriguez, Deborah Cohan, Aaron B. Caughey. .View in: Publisher Site Mentions:
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Delivery options for prevention of perinatal HIV transmission. Am Fam Physician. 2009 Dec 15; 80(12):1356. Fogler J, Cohan D, Weber S, Goldschmidt RH. PMID: 20000297.
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Emergency contraception for newly arrested women: evidence for an unrecognized public health opportunity. J Urban Health. 2010 Mar; 87(2):244-253. Sufrin CB, Tulsky JP, Goldenson J, Winter KS, Cohan DL. PMID: 20012702.
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650: Cost-effectiveness of prenatal HIV screening strategies in Uganda. American Journal of Obstetrics and Gynecology. 2009 Dec 1; 201(6):s236. Lena Kim, Sinae Vogel, Deborah Cohan, Aaron Caughey. .View in: Publisher Site Mentions:
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Placental malaria among HIV-infected and uninfected women receiving anti-folates in a high transmission area of Uganda. Malar J. 2009 Nov 14; 8:254. Newman PM, Wanzira H, Tumwine G, Arinaitwe E, Waldman S, Achan J, Havlir D, Rosenthal PJ, Dorsey G, Clark TD, Cohan D. PMID: 19912657.
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Criminalization, legalization or decriminalization of sex work: what female sex workers say in San Francisco, USA. Reprod Health Matters. 2009 Nov; 17(34):38-46. Lutnick A, Cohan D. PMID: 19962636.
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Patient perspectives with abbreviated versus standard pre-test HIV counseling in the prenatal setting: a randomized-controlled, non-inferiority trial. PLoS One. 2009; 4(4):e5166. Cohan D, Gomez E, Greenberg M, Washington S, Charlebois ED. PMID: 19367335.
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HIV testing attitudes and practices among clinicians in the era of updated Centers for Disease Control and Prevention recommendations. . 2009 Jan 01; 50(1):114-6. Cohan D, Gomez E, Dowling T, Zetola N, Kaplan B, Klausner JD. PMID: 19092452.View in: PubMed Mentions:
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Increased uptake of HIV testing with the integration of nurse-initiated HIV testing into routine prenatal care. . 2008 Dec 15; 49(5):571-3. Cohan D, Sarnquist C, Gomez E, Feakins C, Maldonado Y, Zetola N. PMID: 19202463.View in: PubMed Mentions:
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455: Cost-effectiveness of lamivudine therapy in viremic hepatitis B-infected pregnant women for prevention of vertical transmission of hepatitis B. American Journal of Obstetrics and Gynecology. 2008 Dec 1; 199(6):s136. Natali Aziz, Phuong Nguyen, Alison Cahill, Deborah Cohan, Sarah Little, Aaron Caughey. .View in: Publisher Site Mentions:
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Rapid Human Immunodeficiency Virus Testing on Labor and Delivery. Obstetrics and Gynecology. 2008 Nov 1; 112(5):1181. Lisa Rahangdale, Deborah Cohan. .View in: Publisher Site Mentions:
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Assisted reproduction for couples affected by human immunodeficiency virus in California. Fertil Steril. 2009 Apr; 91(4 Suppl):1540-3. Barnhart N, Shannon M, Weber S, Cohan D. PMID: 18973880.
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Rapid human immunodeficiency virus testing on labor and delivery. Obstet Gynecol. 2008 Jul; 112(1):159-63. Rahangdale L, Cohan D. PMID: 18591321.
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Impact of round-the-clock, rapid oral fluid HIV testing of women in labor in rural India. PLoS Med. 2008 May 06; 5(5):e92. Pai NP, Barick R, Tulsky JP, Shivkumar PV, Cohan D, Kalantri S, Pai M, Klein MB, Chhabra S. PMID: 18462011.
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Patient acceptance of and satisfaction with rapid HIV Testing in a Labor and Delivery Setting. J Womens Health (Larchmt). 2008 Apr; 17(3):465-71. Rahangdale L, Sarnquist C, Maldonado Y, Cohan D. PMID: 18373491.
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Rapid HIV testing on labor and delivery: lessons from the field. . 2007 Nov 01; 46(3):376-8. Rahangdale L, Sarnquist C, Feakins C, Nassos P, Haller B, Cohan D. PMID: 18090304.View in: PubMed Mentions:
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Consultation needs in perinatal HIV care: experience of the National Perinatal HIV Consultation Service. Am J Obstet Gynecol. 2007 Sep; 197(3 Suppl):S137-41. Fogler JA, Weber S, Goldschmidt RH, Mahoney MR, Cohan D. PMID: 17825645.
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Rapid point-of-care HIV testing in pregnant women: a systematic review and meta-analysis. Trop Med Int Health. 2007 Feb; 12(2):162-73. Pai NP, Tulsky JP, Cohan D, Colford JM, Reingold AL. PMID: 17300622.
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Editorial comment: within our reach--the end of perinatal HIV transmission. AIDS Read. 2007 Jan; 17(1):36-7. Cohan D. PMID: 17274146.
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Sex worker health: San Francisco style. Sex Transm Infect. 2006 Oct; 82(5):418-22. Cohan D, Lutnick A, Davidson P, Cloniger C, Herlyn A, Breyer J, Cobaugh C, Wilson D, Klausner J. PMID: 16854996.
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Opportunities to Prevent HIV Transmission in Newborns: In Reply. Pediatrics. 2006 Jul 1; 118(1):437-437. Jessica A. Fogler, Deborah Cohan, Shannon Weber, Ronald H. Goldschmidt. .View in: Publisher Site Mentions:
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Cesarean delivery and perinatal HIV transmission: waiting for definitive data. Clin Infect Dis. 2005 Oct 01; 41(7):1068; author reply 1068-9. Cohan D. PMID: 16142679.
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Health indicators among low income women who report a history of sex work: the population based Northern California Young Women's Survey. Sex Transm Infect. 2005 Oct; 81(5):428-33. Cohan DL, Kim A, Ruiz J, Morrow S, Reardon J, Lynch M, Klausner JD, Molitor F, Allen B, Green Ajufo B, Ferrero D, Bell Sanford G, Page-Shafer K, Delgado V, McFarland W. PMID: 16199746.
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Perinatal transmission of multidrug-resistant HIV-1 despite viral suppression on an enfuvirtide-based treatment regimen. AIDS. 2005 Jun 10; 19(9):989-90. Cohan D, Feakins C, Wara D, Petru A, McNicholl I, Schillinger D, Lu J, Kuritzkes D, Deeks SG. PMID: 15905684.
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Temporal trends in early clinical manifestations of perinatal HIV infection in a population-based cohort. JAMA. 2005 May 11; 293(18):2221-31. Berk DR, Falkovitz-Halpern MS, Hill DW, Albin C, Arrieta A, Bork JM, Cohan D, Nilson B, Petru A, Ruiz J, Weintrub PS, Wenman W, Maldonado YA. PMID: 15886377.
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Rapid HIV tests and counseling for pregnant women for preventing mother-to-child HIV transmission. Cochrane Database of Systematic Reviews. 2005 Jan 24. Mika Nagamine, Nitika Pai, Deborah Cohan. .View in: Publisher Site Mentions:
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Perinatal HIV: special considerations. Top HIV Med. 2003 Nov-Dec; 11(6):200-13. Cohan D. PMID: 14724328.
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Cesarean delivery and risk of herpes simplex virus infection. JAMA. 2003 May 07; 289(17):2208; author reply 2208-9. Cohan D. PMID: 12734124.
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