Publications > HIV and sexually transmitted infections
HIV-positive women using contraceptive implants and efavirenz-based antiretroviral therapy (ART) had a higher risk of contraceptive failure than did those using nevirapine-based ART, but they still had lower contraceptive failure rates than women using any other contraceptive methods except intrauterine devices.
- Patel RC, Onono M, Gandhi M, Blat C, Hagey J, Shade SB, Vittinghoff E, Bukusi EA, Newmann SJ, Cohen CR. The Lancet HIV. October 2015.
Clinicians need to improve their knowledge of hormonal contraceptive options safe for women at high risk of HIV and HIV-positive women. Contraceptive education should be integrated into HIV training.
- Blanchard K, Chipato T, Ramjee G, Nhemachena T, McCulloch C, Grossman D, Morar N, Padian NS, Newmann S, Harper CC. Contraception. May 2014.
There were no differences between these two visual inspection methods in detection rates for high grade cervical cancer. Visual inspection with acetic acid, an easy testing procedure, can be used alone as a cervical cancer screening strategy in low-income settings.
- Huchko MJ, Sneden J, Leslie HH, Abdulrahim N, Maloba M, Bukusi E, Cohen CR. Bulletin of the World Health Organization. March 2014.
Integration of family planning services into HIV care clinics increased use of more effective contraceptive methods with a non-significant reduction in condom use.
- Grossman D, Onono M, Newmann SJ, Blat C, Bukusi EA, Shade SB, Steinfeld RL, Cohen CR. AIDS. October 2013.
Integration of HIV services into primary care services was associated with significant increases in patient satisfaction in certain domains, with no negative effect on satisfaction.
- Odeny TA, Penner J, Lewis-Kulzer J, Leslie HH, Shade SB, Adero W, Kioko J, Cohen CR, Bukusi EA. AIDS Research and Treatment. April 2013.
This is the first randomized trial of antenatal care and HIV service integration to be conducted in rural Africa. The study will provide critical evidence regarding the effectiveness of this strategy, with important implications for programs striving to eliminate mother-to-child HIV transmission.
- Turan JM, Steinfeld RL, Onono M, Bukusi EA, Woods M, Shade SB, Washington S, Marima R, Penner J, Ackers ML, Mbori-Ngacha D, Cohen CR. PLoS One. September 2012.
For pre-exposure prophylaxis (PrEP), both oral tenofovir disoproxil fumarate (TDF) and oral tenofovir-emtricitabine (TDF-FTC) protect against HIV-1 infection in heterosexual men and women.
- Baeten JM, Donnell D, Ndase P, Mugo NR, Campbell JD, Wangisi J, Tappero JW, et al; Partners PrEP Study Team. The New England Journal of Medicine. August 2012.
In serodiscordant partnerships with an HIV-positive female and HIV-negative male, vaginal insemination of a partner's semen during the fertile period coupled with 100% condom use may be the safest method of conception.
- Mmeje O, Cohen CR, Cohan D. Infectious Diseases in Obstetrics & Gynecology. July 2012.
The 0.5% PRO2000 gel demonstrated a modest 30% reduction in HIV acquisition in women.
- Abdool Karim SS, Richardson BA, Ramjee G, Hoffman IF, Chirenje ZM, et al.; HIV Prevention Trials Network (HPTN) 035 Study Team. AIDS. April 2011.
Women are waiting for safe, easy to use, inexpensive and efficacious technologies to help them prevent HIV and other STIs. Probiotics, as a potential live microbicide, offer significant advantages including their safety profile, and a simplified self-replicating drug delivery platform.
- Hemmerling A, Cohen CR. Journal of Acquired Immune Deficiency Syndromes. March 2011.
Higher risk sexual behavior in the context of migration increased women's likelihood of HIV infection.
- Camlin CS, Hosegood V, Newell ML, McGrath N, Bärnighausen T, Snow RC. PLOS ONE. July 2010.
Low CD4 cell counts and high plasma HIV-1 concentrations might guide use of anti-retroviral therapy (ART) to achieve an HIV-1 prevention benefit. Provision of ART to HIV-1 infected patients could be an effective strategy to achieve population-level reductions in HIV-1 transmission.
- Donnell D, Baeten JM, Kiarie J, Thomas KK, Stevens W, Cohen CR, McIntyre J, Lingappa JR, Celum C. Lancet. June 2010.
Microbicide acceptability for youth in sub-Saharan Africa may be bolstered by desperation for new methods to stop the spread of HIV, yet hindered by misgivings about experimental HIV prevention methods for youth.
- Montandon M, Sahin-Hodoglugil NN, Bukusi E, Agot K, Boland B, Cohen CR. Sex Health. December 2008.